Prokidney (PROK) Operating Margin (2024 - 2026)

Prokidney (PROK) reported Operating Margin of 19881.86% for Q1 2026, down 188708.0% year-over-year from N/an in Q1 2025, and down 150.9% on a QoQ basis from 39059.56% in Q4 2025.

Prokidney (PROK) has 3 years of Operating Margin data on file, last reported at 19881.86% in Q1 2026.

  • Quarterly Operating Margin fell 188708.0% year-over-year to 19881.86% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 3970.42% (up 5648318.0% YoY) and the FY2025 annual result came in at 3555.66%, up 23812329.0% from the prior year.
  • Operating Margin slipped to 19881.86% in Q1 2026 per PROK's latest filing, from 39059.56% in the prior quarter.
  • Across five years, Operating Margin topped out at 39059.56% in Q4 2025 and bottomed at 67856.58% in Q4 2024.
  • The 3-year median for Operating Margin is 17981.33% (2025), against an average of 17066.91%.
  • The widest annual swing landed in 2025, when Operating Margin soared 10691613 bps; it then tumbled 188708 bps in 2026.
  • Tracing PROK's Operating Margin over 3 years: stood at 67856.58% in 2024, then surged by 158 bps to 39059.56% in 2025, then plunged by 151 bps to 19881.86% in 2026.
  • Per Business Quant, the three latest PROK Operating Margin figures stand at 19881.86% (Q1 2026), 39059.56% (Q4 2025), and 17759.91% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 23.02%
10 Prokidney 259.72 Mn 1.55 Bn - -19,881.86%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -19,881.86%
Dec 31, 2025 39,059.56%
Sep 30, 2025 -17,759.91%
Jun 30, 2025 -17,967.87%
Mar 31, 2025 -17,994.78%
Dec 31, 2024 -67,856.58%