Prokidney (PROK) Operating Margin (2024 - 2026)
Prokidney (PROK) posted quarterly Operating Margin of 19881.86% for Q1 2026, down 188708.0% year-over-year from N/an in Q1 2025, and up 1.4% quarter-over-quarter from 20164.89% in Q4 2025.
Prokidney (PROK) Operating Margin (2024 - 2026) Analysis & Trends
Prokidney (PROK) has reported Operating Margin for 3 consecutive years, with 19881.86% the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Margin fell 188708.0% year-over-year to 19881.86%; the TTM figure through Mar 2026 stood at 18959.73% (up 4149386.0% YoY), while the FY2025 annual figure was 18477.83%, up 22320112.0% from the prior year.
- Operating Margin advanced to 19881.86% in Q1 2026 per PROK's latest filing, from 20164.89% in the prior quarter.
- Across five years, Operating Margin topped out at 17759.91% in Q3 2025 and bottomed at 67856.58% in Q4 2024.
- Historically, Operating Margin has averaged 26937.65% across 3 years, with a median of 18938.32% in 2025.
- Annual changes were most pronounced in 2025 — Operating Margin jumped 4769169 bps — and 2026, when it sank 188708 bps.
- Prokidney's Operating Margin stood at 67856.58% in 2024, then surged by 70 bps to 20164.89% in 2025, then advanced by 1 bps to 19881.86% in 2026.
- Business Quant data shows PROK's Operating Margin at 19881.86% in Q1 2026, 20164.89% in Q4 2025, and 17759.91% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 31.68% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 19.06% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -105.20% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 19.75% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 17.93% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -0.36% |
| 10 | Prokidney | 679.95 Mn | 679.95 Mn | - | -32,248.67% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -32,248.67% |
| Mar 31, 2026 | -19,881.86% |
| Dec 31, 2025 | -20,164.89% |
| Sep 30, 2025 | -17,759.91% |
| Jun 30, 2025 | -17,967.87% |
| Mar 31, 2025 | -17,994.78% |
| Dec 31, 2024 | -67,856.58% |