Prelude Therapeutics (PRLD) Operating Margin (2024 - 2026)
Prelude Therapeutics (PRLD) recorded Operating Margin of -270.93% in Q2 2026, up 38.61 percentage points from the prior quarter.
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Analysis
Prelude Therapeutics (PRLD) Operating Margin (2024 - 2026) Analysis & Trends
On a TTM basis, Prelude Therapeutics' Operating Margin came in at -300.56% as of Jun 30, 2026, up 1628.11 percentage points year-over-year; for FY2025, it came in at -861.33%, up 1134.58 percentage points from FY2024.
- Across earlier years, Operating Margin came in at -1995.91% in FY2024.
- Per Business Quant, the preceding three quarters came in at -309.54% (Q1 2026), -307.59% (Q4 2025) and -314.12% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Prelude Therapeutics | 312.03 Mn | -285.27 Mn | - | -270.93% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -270.93% |
| Mar 31, 2026 | -309.54% |
| Dec 31, 2025 | -307.59% |
| Sep 30, 2025 | -314.12% |
| Dec 31, 2024 | -845.78% |
| Sep 30, 2024 | -1,145.87% |
API Access
Prelude Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=PRLD&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "PRLD", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=PRLD&period=max&api_key=YOUR_API_KEY");
const data = await res.json();