Puma Biotechnology (PBYI) Operating Margin (2017 - 2026)
Puma Biotechnology's Operating Margin was 13.42% in Q2 2026, up 0.77 percentage points from 12.66% a year earlier and up 21.97 percentage points from the prior quarter.
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Analysis
Puma Biotechnology (PBYI) Operating Margin (2017 - 2026) Analysis & Trends
On a trailing twelve-month basis, Puma Biotechnology's Operating Margin was 13.16% through Jun 30, 2026, down 6.19 percentage points year-over-year; for FY2025, it was 16.33%, up 2.90 percentage points from FY2024.
- Operating Margin shows a five-year change of +29.84 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was 13.44% in FY2024 (-0.42 pp), 13.85% in FY2023 (+3.45 pp), 10.40% in FY2022 (+9.89 pp) and 0.51% in FY2021 (+14.01 pp).
- Quarterly Operating Margin has moved between -19.36% (Q3 2021) and 27.41% (Q3 2024) over five years.
- Compared with a year earlier, Operating Margin was higher in six of the last eight quarters, with an average year-over-year change of +2.40 percentage points.
- The best year-over-year quarter for Operating Margin over five years was Q2 2022 (a gain of 51.42 percentage points); the worst was Q1 2022 (a drop of 22.16 percentage points).
- Per Business Quant data, PBYI's Operating Margin in the three quarters before Q2 2026 was -8.54% (Q1 2026), 22.67% (Q4 2025) and 17.57% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Puma Biotechnology | 499.78 Mn | 112.42 Mn | 44.03 Mn | 13.42% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 13.42% |
| Mar 31, 2026 | -8.54% |
| Dec 31, 2025 | 22.67% |
| Sep 30, 2025 | 17.57% |
| Jun 30, 2025 | 12.66% |
| Mar 31, 2025 | 8.66% |
| Dec 31, 2024 | 22.62% |
| Sep 30, 2024 | 27.41% |
| Jun 30, 2024 | -4.63% |
| Mar 31, 2024 | -5.25% |
| Dec 31, 2023 | 20.50% |
| Sep 30, 2023 | 15.30% |
| Jun 30, 2023 | 8.96% |
| Mar 31, 2023 | 8.27% |
| Dec 31, 2022 | 15.25% |
| Sep 30, 2022 | 4.19% |
| Jun 30, 2022 | 20.26% |
| Mar 31, 2022 | -1.63% |
| Dec 31, 2021 | 12.34% |
| Sep 30, 2021 | -19.36% |
API Access
Puma Biotechnology Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=PBYI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "PBYI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=PBYI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();