Puma Biotechnology PBYI Institutional Ownership

Updated Oct 11, 2026

Puma Biotechnology, Inc. (NASDAQ:PBYI) was held by 161 institutional investors that filed 13F reports for the quarter ended June 30, 2026.

• Their combined stake equaled 75.64% of outstanding shares in Q2 2026, up from 74.41% in Q1 2026.
• Total shares held in Puma Biotechnology rose 2.10% from Q1 2026, while the number of holders rose 35.29% from Q2 2025.
• Of the 161 holders of PBYI in Q2 2026, 82 added to their positions, 52 reduced their stakes and 27 left their positions unchanged.
• The aggregate institutional position in Puma Biotechnology was 38.66Mn shares at the end of Q2 2026, up 795.33K from the prior quarter and up 6.66Mn from a year earlier.
• As of June 30, 2026, the biggest holder of Puma Biotechnology was Acorn Capital Advisors, LLC with 4.13Mn shares, or 8.08% of shares outstanding.
• The biggest increases in PBYI positions during Q2 2026 came from LSV Asset Management (+435.11K shares), American Century Companies Inc (+403.65K shares), Geode Capital Management, LLC (+322.06K shares), Invesco Ltd. (+205.96K shares) and BlackRock, Inc. (+205.78K shares).
• The biggest cuts to PBYI positions during Q2 2026 came from Millennium Management LLC (-875.28K shares), Connor, Clark & Lunn Investment Management Ltd. (-139.85K shares), Renaissance Technologies LLC (-106.2K shares), Morgan Stanley (-94.07K shares) and SEI Investments Co (-89.51K shares).
• Per Business Quant data, the 10 largest holders of Puma Biotechnology at the end of Q2 2026 were Acorn Capital Advisors, LLC (4.13Mn shares), BlackRock, Inc. (3.8Mn shares), American Century Companies Inc (2.32Mn shares), Acadian Asset Management LLC (2.05Mn shares), Renaissance Technologies LLC (1.84Mn shares), Vanguard Capital Management LLC (1.84Mn shares), Vanguard Portfolio Management LLC (1.83Mn shares), LSV Asset Management (1.62Mn shares), Dimensional Fund Advisors LP (1.52Mn shares) and Geode Capital Management, LLC (1.34Mn shares).