Vertex Pharmaceuticals (VRTX) Enterprise Value (2009 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Enterprise Value of -$7.2 billion in Q1 2026, down 9.66% quarter-over-quarter from -$6.6 billion in Q4 2025, and down 16.86% on a YoY basis from -$8.7 billion in Q1 2025.

Vertex Pharmaceuticals (VRTX) Enterprise Value (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Enterprise Value history runs 18 years deep, the most recent figure standing at -$7.2 billion for Q1 2026.

  • In Q1 2026, Enterprise Value fell 16.86% year-over-year to -$7.2 billion; the TTM figure through Mar 2026 stood at -$7.2 billion (down 16.86% YoY), while the FY2025 annual figure was -$6.6 billion, down 8.05% from the prior year.
  • Enterprise Value was -$7.2 billion for Q1 2026 at Vertex Pharmaceuticals, down from -$6.6 billion in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$5.8 billion in Q2 2024 to a low of -$11.9 billion in Q3 2023.
  • Historically, Enterprise Value has averaged -$8.5 billion across 5 years, with a median of -$8.2 billion in 2022.
  • The sharpest annual moves came in 2022 and 2024: Enterprise Value plunged 43.24% in 2022, then surged 48.42% in 2024.
  • A 5-year view of Enterprise Value shows it stood at -$10.8 billion in 2022, then fell by 4.08% to -$11.2 billion in 2023, then soared by 45.48% to -$6.1 billion in 2024, then retreated by 8.05% to -$6.6 billion in 2025, then dropped by 9.66% to -$7.2 billion in 2026.
  • The last three Enterprise Value figures came in at -$7.2 billion (Q1 2026), -$6.6 billion (Q4 2025), and -$6.3 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn -8.75 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -7.25 Bn
Dec 31, 2025 -6.61 Bn
Sep 30, 2025 -6.29 Bn
Jun 30, 2025 -6.38 Bn
Mar 31, 2025 -6.20 Bn
Dec 31, 2024 -6.12 Bn
Sep 30, 2024 -6.52 Bn
Jun 30, 2024 -5.80 Bn
Mar 31, 2024 -10.17 Bn
Dec 31, 2023 -11.22 Bn
Sep 30, 2023 -11.93 Bn
Jun 30, 2023 -11.24 Bn
Mar 31, 2023 -10.41 Bn
Dec 31, 2022 -10.78 Bn
Sep 30, 2022 -9.77 Bn
Jun 30, 2022 -9.25 Bn
Mar 31, 2022 -8.24 Bn
Dec 31, 2021 -7.52 Bn
Sep 30, 2021 -6.96 Bn
Jun 30, 2021 -6.71 Bn