Vertex Pharmaceuticals (VRTX) Enterprise Value (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Enterprise Value came in at -$7.2 billion in Q1 2026, down 16.86% year-on-year from -$8.7 billion in Q1 2025, and down 9.66% quarter-over-quarter from -$6.6 billion in Q4 2025.

Vertex Pharmaceuticals (VRTX) Enterprise Value (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Enterprise Value history runs 18 years deep, the most recent figure standing at -$7.2 billion for Q1 2026.

  • On a quarterly basis, Enterprise Value fell 16.86% year-over-year to -$7.2 billion in Q1 2026; TTM through Mar 2026 was -$7.2 billion, a 16.86% decrease from a year earlier, with the FY2025 full-year figure at -$6.6 billion, down 8.05% from the prior year.
  • Enterprise Value fell to -$7.2 billion in Q1 2026 per VRTX's latest filing, from -$6.6 billion in the prior quarter.
  • Across five years, Enterprise Value topped out at -$5.8 billion in Q2 2024 and bottomed at -$11.9 billion in Q3 2023.
  • The 5-year median for Enterprise Value is -$8.2 billion (2022), against an average of -$8.5 billion.
  • Across the five-year window, Enterprise Value plunged 43.24% in 2022 and jumped 48.42% in 2024, its largest moves.
  • Year by year, Enterprise Value stood at -$10.8 billion in 2022, then fell by 4.08% to -$11.2 billion in 2023, then soared by 45.48% to -$6.1 billion in 2024, then retreated by 8.05% to -$6.6 billion in 2025, then dropped by 9.66% to -$7.2 billion in 2026.
  • Per Business Quant, the three latest VRTX Enterprise Value figures stand at -$7.2 billion (Q1 2026), -$6.6 billion (Q4 2025), and -$6.3 billion (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -283.54 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -61.40 Mn
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.83 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn -4.79 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -1.91 Bn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn -3.01 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -7.25 Bn
Dec 31, 2025 -6.61 Bn
Sep 30, 2025 -6.29 Bn
Jun 30, 2025 -6.38 Bn
Mar 31, 2025 -6.20 Bn
Dec 31, 2024 -6.12 Bn
Sep 30, 2024 -6.52 Bn
Jun 30, 2024 -5.80 Bn
Mar 31, 2024 -10.17 Bn
Dec 31, 2023 -11.22 Bn
Sep 30, 2023 -11.93 Bn
Jun 30, 2023 -11.24 Bn
Mar 31, 2023 -10.41 Bn
Dec 31, 2022 -10.78 Bn
Sep 30, 2022 -9.77 Bn
Jun 30, 2022 -9.25 Bn
Mar 31, 2022 -8.24 Bn
Dec 31, 2021 -7.52 Bn
Sep 30, 2021 -6.96 Bn
Jun 30, 2021 -6.71 Bn