Growth Metrics

BioNTech SE (BNTX) Enterprise Value (2018 - 2025)

BioNTech SE (BNTX) posted Enterprise Value of -$20.1 billion for Q4 2025, down 18.54% on a QoQ basis from -$17.0 billion in Q3 2025, and down 12.25% year-over-year from -$22.9 billion in Q4 2024.

BioNTech SE (BNTX) has 8 years of Enterprise Value data on file, last reported at -$20.1 billion in Q4 2025.

  • In Q4 2025, Enterprise Value fell 12.25% year-over-year to -$20.1 billion; the TTM figure through Dec 2025 stood at -$20.1 billion (down 12.25% YoY), while the FY2025 annual figure was -$19.5 billion, down 8.95% from the prior year.
  • Enterprise Value declined to -$20.1 billion in Q4 2025, from -$17.0 billion in the prior quarter.
  • Across five years, Enterprise Value topped out at -$1.4 billion in Q3 2021 and bottomed at -$1459786.9 billion in Q1 2021.
  • A 5-year average of -$73096.8 billion and a median of -$16.8 billion in 2023 frame the typical range for Enterprise Value.
  • The widest YoY moves for Enterprise Value: up 99.87% in 2022, down 563.22% in 2022.
  • Year by year, Enterprise Value stood at -$2.4 billion in 2021, then sank by 504.7% to -$14.3 billion in 2022, then slipped by 24.09% to -$17.8 billion in 2023, then declined by 0.73% to -$17.9 billion in 2024, then slipped by 12.25% to -$20.1 billion in 2025.
  • The last three Enterprise Value figures came in at -$20.1 billion (Q4 2025), -$17.0 billion (Q3 2025), and -$15.9 billion (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.32 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -3.01 Bn
10 BioNTech SE 27.66 Bn 7.53 Bn 668.28 Mn -20.13 Bn

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -17.32 Bn
Sep 30, 2025 -17.19 Bn
Jun 30, 2025 -15.79 Bn
Mar 31, 2025 -14.40 Bn
Dec 31, 2024 -19.97 Bn
Sep 30, 2024 -20.59 Bn
Jun 30, 2024 -20.01 Bn
Mar 31, 2024 -19.94 Bn
Dec 31, 2023 -20.19 Bn
Sep 30, 2023 -17.87 Bn
Jun 30, 2023 -16.62 Bn
Mar 31, 2023 -15.45 Bn
Dec 31, 2022 -14.35 Bn
Sep 30, 2022 -9.47 Bn
Jun 30, 2022 -6.58 Bn
Mar 31, 2022 -1.95 Bn
Dec 31, 2021 -2.37 Bn
Sep 30, 2021 -1.43 Bn
Jun 30, 2021 -1.46 Bn
Mar 31, 2021 -1,459,786.94 Bn
Dec 31, 2020 -1.61 Bn
Dec 31, 2019 -576.44 Mn
Sep 30, 2019 -515.93 Mn
Dec 31, 2018 -469.10 Mn
Sep 30, 2018 -200.18 Mn