BioNTech SE (BNTX) Enterprise Value (2018 - 2025)

BioNTech SE (BNTX) posted Enterprise Value of -$18.4 billion for Q4 2025, down 8.3% sequentially from -$17.0 billion in Q3 2025, and up 5.67% YoY from -$17.4 billion in Q4 2024.

BioNTech SE (BNTX) Enterprise Value (2018 - 2025) Analysis & Trends

BioNTech SE has reported Enterprise Value for 8 years, with the latest figure at -$18.4 billion in Q4 2025.

  • Quarterly Enterprise Value rose 5.67% year-over-year to -$18.4 billion in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$18.4 billion (up 5.67% YoY) and the FY2025 annual result came in at -$17.9 billion, up 8.44% from the prior year.
  • Enterprise Value slipped to -$18.4 billion in Q4 2025 per BNTX's latest filing, from -$17.0 billion in the prior quarter.
  • Over five years, Enterprise Value peaked at -$432.8 million in Q3 2021 and troughed at -$19.5 billion in Q4 2024.
  • A 5-year average of -$12.1 billion and a median of -$15.4 billion in 2025 frame the typical range for Enterprise Value.
  • The widest YoY moves for Enterprise Value: up 15.45% in 2022, down 3039.57% in 2022.
  • Over 5 years, Enterprise Value stood at -$2.4 billion in 2021, then slumped by 504.7% to -$14.3 billion in 2022, then decreased by 24.09% to -$17.8 billion in 2023, then dropped by 9.51% to -$19.5 billion in 2024, then advanced by 5.67% to -$18.4 billion in 2025.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$18.4 billion, -$17.0 billion, and -$15.9 billion for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 BioNTech SE 23.54 Bn 5.15 Bn 668.28 Mn -18.39 Bn

Historic Data

Download Data
DateValue
Dec 31, 2025 -17.32 Bn
Sep 30, 2025 -16.98 Bn
Jun 30, 2025 -15.89 Bn
Mar 31, 2025 -14.84 Bn
Dec 31, 2024 -17.93 Bn
Sep 30, 2024 -18.35 Bn
Jun 30, 2024 -18.63 Bn
Mar 31, 2024 -17.02 Bn
Dec 31, 2023 -17.81 Bn
Sep 30, 2023 -17.14 Bn
Jun 30, 2023 -16.94 Bn
Mar 31, 2023 -13.59 Bn
Dec 31, 2022 -14.35 Bn
Sep 30, 2022 -1.33 Bn
Jun 30, 2022 -1.49 Bn
Mar 31, 2022 -1.96 Bn
Dec 31, 2021 -2.37 Bn
Sep 30, 2021 -432.80 Mn
Jun 30, 2021 -1.76 Bn
Mar 31, 2021 -920.96 Mn