Growth Metrics

Alnylam Pharmaceuticals (ALNY) Enterprise Value (2009 - 2026)

Alnylam Pharmaceuticals posted quarterly Enterprise Value of -$3.0 billion for Q1 2026, down 193.05% year-on-year from $3.2 billion in Q1 2025, and down 3.46% on a QoQ basis from -$2.9 billion in Q4 2025.

Alnylam Pharmaceuticals (ALNY) has 18 years of Enterprise Value data on file, last reported at -$3.0 billion in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value fell 193.05% year-over-year to -$3.0 billion; the trailing twelve-month figure through Mar 2026 stood at -$3.0 billion (down 193.05% YoY), and the FY2025 full-year result was -$2.9 billion, down 197.75% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$3.0 billion, down from -$2.9 billion in the prior quarter.
  • Across five years, Enterprise Value topped out at -$685.1 million in Q2 2023 and bottomed at -$3.0 billion in Q1 2026.
  • The 5-year median for Enterprise Value is -$2.2 billion (2022), against an average of -$2.0 billion.
  • The widest annual swing landed in 2023, when Enterprise Value jumped 67.06%; it then plunged 281.69% in 2024.
  • A 5-year view of Enterprise Value shows it stood at -$896.7 million in 2022, then slumped by 170.8% to -$2.4 billion in 2023, then soared by 59.77% to -$976.8 million in 2024, then plunged by 197.75% to -$2.9 billion in 2025, then dropped by 3.46% to -$3.0 billion in 2026.
  • The last three Enterprise Value figures came in at -$3.0 billion (Q1 2026), -$2.9 billion (Q4 2025), and -$2.7 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.32 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -3.01 Bn
10 Revolution Medicines 32.39 Bn 32.39 Bn - -1.91 Bn

Historic Data

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DateValue
Mar 31, 2026 -3.01 Bn
Dec 31, 2025 -2.91 Bn
Sep 30, 2025 -2.72 Bn
Jun 30, 2025 -2.86 Bn
Mar 31, 2025 -1.03 Bn
Dec 31, 2024 -976.81 Mn
Sep 30, 2024 -1.11 Bn
Jun 30, 2024 -2.61 Bn
Mar 31, 2024 -2.36 Bn
Dec 31, 2023 -2.43 Bn
Sep 30, 2023 -2.40 Bn
Jun 30, 2023 -685.06 Mn
Mar 31, 2023 -2.04 Bn
Dec 31, 2022 -896.68 Mn
Sep 30, 2022 -2.24 Bn
Jun 30, 2022 -2.08 Bn
Mar 31, 2022 -2.21 Bn
Dec 31, 2021 -2.37 Bn
Sep 30, 2021 -1.17 Bn
Jun 30, 2021 -798.30 Mn
Mar 31, 2021 -1.65 Bn
Dec 31, 2020 -1.83 Bn
Sep 30, 2020 -1.78 Bn
Jun 30, 2020 -1.84 Bn
Mar 31, 2020 -1.30 Bn
Dec 31, 2019 -1.52 Bn
Sep 30, 2019 -1.72 Bn
Jun 30, 2019 -1.93 Bn
Mar 31, 2019 -1.24 Bn
Dec 31, 2018 -1.09 Bn
Sep 30, 2018 -331.61 Mn
Jun 30, 2018 -373.50 Mn
Mar 31, 2018 -1.57 Bn
Dec 31, 2017 -1.69 Bn
Sep 30, 2017 -948.29 Mn
Jun 30, 2017 -923.27 Mn
Mar 31, 2017 -556.92 Mn
Dec 31, 2016 -619.27 Mn
Sep 30, 2016 -699.52 Mn
Jun 30, 2016 -843.07 Mn
Mar 31, 2016 -265.21 Mn
Dec 31, 2015 -232.31 Mn
Sep 30, 2015 -187.78 Mn
Jun 30, 2015 -215.89 Mn
Mar 31, 2015 -966.98 Mn
Dec 31, 2014 -602.11 Mn
Sep 30, 2014 -590.65 Mn
Jun 30, 2014 -605.31 Mn
Mar 31, 2014 -665.49 Mn
Dec 31, 2013 -245.87 Mn
Sep 30, 2013 -193.78 Mn
Jun 30, 2013 -209.69 Mn
Mar 31, 2013 -236.01 Mn
Dec 31, 2012 -122.81 Mn
Sep 30, 2012 -228.34 Mn
Jun 30, 2012 -48.27 Mn
Mar 31, 2012 -199.10 Mn
Dec 31, 2011 -146.40 Mn
Sep 30, 2011 -173.02 Mn
Jun 30, 2011 -217.95 Mn
Mar 31, 2011 -244.64 Mn
Dec 31, 2010 -233.13 Mn
Sep 30, 2010 -231.37 Mn
Jun 30, 2010 -259.19 Mn
Mar 31, 2010 -114.95 Mn
Dec 31, 2009 -281.40 Mn
Sep 30, 2009 -98.09 Mn
Jun 30, 2009 -147.87 Mn