Alnylam Pharmaceuticals (ALNY) Enterprise Value (2009 - 2026)

Alnylam Pharmaceuticals (ALNY) posted Enterprise Value of -$3.0 billion for Q1 2026, down 3.46% on a QoQ basis from -$2.9 billion in Q4 2025, and down 14.64% year-over-year from -$3.5 billion in Q1 2025.

Alnylam Pharmaceuticals (ALNY) Enterprise Value (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals' Enterprise Value history runs 18 years deep, the most recent figure standing at -$3.0 billion for Q1 2026.

  • Quarterly Enterprise Value fell 14.64% year-over-year to -$3.0 billion in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$3.0 billion (down 14.64% YoY) and the FY2025 annual result came in at -$2.9 billion, down 197.75% from the prior year.
  • Enterprise Value was -$3.0 billion for Q1 2026 at Alnylam Pharmaceuticals, down from -$2.9 billion in the prior quarter.
  • Across five years, Enterprise Value topped out at -$606.5 million in Q2 2022 and bottomed at -$3.0 billion in Q1 2026.
  • A 5-year average of -$1.6 billion and a median of -$1.1 billion in 2025 frame the typical range for Enterprise Value.
  • Annual changes were most pronounced in 2022 — Enterprise Value slumped 405.73% — and 2023, when it surged 68.38%.
  • Alnylam Pharmaceuticals' Enterprise Value stood at -$2.2 billion in 2022, then dropped by 12.08% to -$2.4 billion in 2023, then jumped by 59.77% to -$976.8 million in 2024, then tumbled by 197.75% to -$2.9 billion in 2025, then declined by 3.46% to -$3.0 billion in 2026.
  • Business Quant data shows ALNY's Enterprise Value at -$3.0 billion in Q1 2026, -$2.9 billion in Q4 2025, and -$1.5 billion in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -283.54 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -61.40 Mn
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.83 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn -4.79 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -1.91 Bn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn -3.01 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -3.01 Bn
Dec 31, 2025 -2.91 Bn
Sep 30, 2025 -1.49 Bn
Jun 30, 2025 -1.11 Bn
Mar 31, 2025 -2.63 Bn
Dec 31, 2024 -976.81 Mn
Sep 30, 2024 -1.11 Bn
Jun 30, 2024 -2.61 Bn
Mar 31, 2024 -693.14 Mn
Dec 31, 2023 -2.43 Bn
Sep 30, 2023 -1.04 Bn
Jun 30, 2023 -685.06 Mn
Mar 31, 2023 -698.10 Mn
Dec 31, 2022 -2.17 Bn
Sep 30, 2022 -1.10 Bn
Jun 30, 2022 -606.46 Mn
Mar 31, 2022 -2.21 Bn
Dec 31, 2021 -889.13 Mn
Sep 30, 2021 -1.17 Bn
Jun 30, 2021 -798.30 Mn