Growth Metrics

Krystal Biotech (KRYS) Operating Margin (2021 - 2025)

Historic Operating Margin for Krystal Biotech (KRYS) over the last 4 years, with Q4 2025 value amounting to 41.33%.

  • Krystal Biotech's Operating Margin fell 40800.0% to 41.33% in Q4 2025 from the same period last year, while for Dec 2025 it was 41.41%, marking a year-over-year increase of 187800.0%. This contributed to the annual value of 41.45% for FY2025, which is 188200.0% up from last year.
  • As of Q4 2025, Krystal Biotech's Operating Margin stood at 41.33%, which was down 40800.0% from 42.3% recorded in Q3 2025.
  • In the past 5 years, Krystal Biotech's Operating Margin ranged from a high of 962.0% in Q1 2021 and a low of 303.8% during Q3 2023
  • Its 4-year average for Operating Margin is 81.92%, with a median of 40.93% in 2025.
  • In the last 5 years, Krystal Biotech's Operating Margin soared by 3306000bps in 2024 and then plummeted by -40800bps in 2025.
  • Quarter analysis of 4 years shows Krystal Biotech's Operating Margin stood at 962.0% in 2021, then crashed by -99bps to 7.71% in 2023, then skyrocketed by 489bps to 45.41% in 2024, then decreased by -9bps to 41.33% in 2025.
  • Its Operating Margin stands at 41.33% for Q4 2025, versus 42.3% for Q3 2025 and 40.93% for Q2 2025.