Ginkgo Bioworks Holdings (DNA) Operating Margin (2020 - 2026)

Ginkgo Bioworks Holdings (DNA) reported Operating Margin of 366.51% for Q1 2026, down 15471.0% on a YoY basis from N/an in Q1 2025, and down 73.0% quarter-over-quarter from 211.86% in Q4 2025.

Ginkgo Bioworks Holdings (DNA) Operating Margin (2020 - 2026) Analysis & Trends

Ginkgo Bioworks Holdings has reported Operating Margin for 7 years, with the latest figure at 366.51% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin fell 15471.0% year-over-year to 366.51%; the trailing twelve-month figure through Mar 2026 stood at 210.66% (down 711.0% YoY), and the FY2025 full-year result was 185.29%, up 6125.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 366.51%, down from 211.86% in the prior quarter.
  • The five-year high for Operating Margin was 61.99% in Q3 2024, with the low at 986.38% in Q3 2022.
  • Historically, Operating Margin has averaged 347.85% across 5 years, with a median of 267.34% in 2023.
  • The largest YoY upside for Operating Margin was 89966 bps in 2022 against a maximum downside of 95202 bps in 2022.
  • Ginkgo Bioworks Holdings' Operating Margin stood at 234.89% in 2022, then slumped by 118 bps to 512.49% in 2023, then soared by 54 bps to 236.29% in 2024, then advanced by 10 bps to 211.86% in 2025, then plunged by 73 bps to 366.51% in 2026.
  • The last three Operating Margin figures came in at 366.51% (Q1 2026), 211.86% (Q4 2025), and 231.78% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Ginkgo Bioworks Holdings 546.79 Mn 546.79 Mn 16.38 Mn -366.51%

Historic Data

Download Data
DateValue
Mar 31, 2026 -366.51%
Dec 31, 2025 -211.86%
Sep 30, 2025 -231.78%
Jun 30, 2025 -132.13%
Mar 31, 2025 -211.80%
Dec 31, 2024 -236.29%
Sep 30, 2024 -61.99%
Jun 30, 2024 -396.66%
Mar 31, 2024 -469.12%
Dec 31, 2023 -512.49%
Sep 30, 2023 -516.68%
Jun 30, 2023 -228.57%
Mar 31, 2023 -267.34%
Dec 31, 2022 -234.89%
Sep 30, 2022 -986.38%
Jun 30, 2022 -447.92%
Mar 31, 2022 -401.04%
Dec 31, 2021 -1,134.55%
Sep 30, 2021 -34.37%
Jun 30, 2021 -137.38%