Ginkgo Bioworks Holdings (DNA) Operating Margin (2020 - 2026)

Ginkgo Bioworks Holdings posted quarterly Operating Margin of 366.51% for Q1 2026, down 15471.0% year-on-year from N/an in Q1 2025, and down 73.0% on a QoQ basis from 211.86% in Q4 2025.

Ginkgo Bioworks Holdings (DNA) has 7 years of Operating Margin data on file, last reported at 366.51% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin fell 15471.0% year-over-year to 366.51%; the trailing twelve-month figure through Mar 2026 stood at 210.66% (down 711.0% YoY), and the FY2025 full-year result was 185.29%, up 6125.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 366.51%, down from 211.86% in the prior quarter.
  • Across five years, Operating Margin topped out at 61.99% in Q3 2024 and bottomed at 986.38% in Q3 2022.
  • The 5-year median for Operating Margin is 267.34% (2023), against an average of 347.85%.
  • Peak annual rise in Operating Margin reached 89966 bps in 2022, while the deepest fall reached 95202 bps in 2022.
  • A 5-year view of Operating Margin shows it stood at 234.89% in 2022, then sank by 118 bps to 512.49% in 2023, then jumped by 54 bps to 236.29% in 2024, then climbed by 10 bps to 211.86% in 2025, then tumbled by 73 bps to 366.51% in 2026.
  • The last three Operating Margin figures came in at 366.51% (Q1 2026), 211.86% (Q4 2025), and 231.78% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 23.02%
10 Ginkgo Bioworks Holdings 542.03 Mn 542.03 Mn 16.38 Mn -366.51%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -366.51%
Dec 31, 2025 -211.86%
Sep 30, 2025 -231.78%
Jun 30, 2025 -132.13%
Mar 31, 2025 -211.80%
Dec 31, 2024 -236.29%
Sep 30, 2024 -61.99%
Jun 30, 2024 -396.66%
Mar 31, 2024 -469.12%
Dec 31, 2023 -512.49%
Sep 30, 2023 -516.68%
Jun 30, 2023 -228.57%
Mar 31, 2023 -267.34%
Dec 31, 2022 -234.89%
Sep 30, 2022 -986.38%
Jun 30, 2022 -447.92%
Mar 31, 2022 -401.04%
Dec 31, 2021 -1,134.55%
Sep 30, 2021 -34.37%
Jun 30, 2021 -137.38%
Mar 31, 2021 -129.52%
Dec 31, 2020 -174.33%
Sep 30, 2020 -258.71%