Ginkgo Bioworks Holdings (DNA) Operating Margin (2020 - 2025)

Ginkgo Bioworks Holdings' Operating Margin history spans 6 years, with the latest figure at 211.86% for Q4 2025.

  • For Q4 2025, Operating Margin rose 2443.0% year-over-year to 211.86%; the TTM value through Dec 2025 reached 185.29%, up 6125.0%, while the annual FY2025 figure was 185.29%, 6125.0% up from the prior year.
  • Operating Margin reached 211.86% in Q4 2025 per DNA's latest filing, up from 231.78% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 34.37% in Q3 2021 to a low of 1134.55% in Q4 2021.
  • Average Operating Margin over 5 years is 347.75%, with a median of 235.59% recorded in 2022.
  • Peak YoY movement for Operating Margin: plummeted -96021bps in 2021, then surged 89966bps in 2022.
  • A 5-year view of Operating Margin shows it stood at 1134.55% in 2021, then skyrocketed by 79bps to 234.89% in 2022, then tumbled by -118bps to 512.49% in 2023, then surged by 54bps to 236.29% in 2024, then grew by 10bps to 211.86% in 2025.
  • Per Business Quant, the three most recent readings for DNA's Operating Margin are 211.86% (Q4 2025), 231.78% (Q3 2025), and 132.13% (Q2 2025).