Ginkgo Bioworks Holdings (DNA) Operating Margin (2020 - 2026)
Ginkgo Bioworks Holdings' Operating Margin was -290.47% in Q2 2026, down 141.85 percentage points from -148.63% a year earlier but up 76.03 percentage points from the prior quarter.
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Analysis
Ginkgo Bioworks Holdings (DNA) Operating Margin (2020 - 2026) Analysis & Trends
On a trailing twelve-month basis, Ginkgo Bioworks Holdings' Operating Margin was -259.86% through Jun 30, 2026, down 118.16 percentage points year-over-year; for FY2025, it was -185.29%, up 61.25 percentage points from FY2024.
- Operating Margin has now increased for four consecutive years, though with a five-year change of -6.54 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -246.54% in FY2024 (+97.22 pp), -343.76% in FY2023 (+118.65 pp), -462.41% in FY2022 (+120.21 pp) and -582.62% in FY2021 (-403.86 pp).
- Quarterly Operating Margin has moved between -1134.55% (Q4 2021) and -34.37% (Q3 2021) over five years.
- Compared with a year earlier, Operating Margin was higher in five of the last eight quarters, with an average year-over-year change of +99.29 percentage points.
- The best year-over-year quarter for Operating Margin over five years was Q4 2022 (a gain of 899.66 percentage points); the worst was Q4 2021 (a drop of 960.21 percentage points).
- Per Business Quant data, DNA's Operating Margin in the three quarters before Q2 2026 was -366.51% (Q1 2026), -211.86% (Q4 2025) and -231.78% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Iqvia Holdings | 44.55 Bn | 36.39 Bn | 1.44 Bn | 11.58% |
| 2 | Medpace Holdings | 17.19 Bn | 15.25 Bn | 201.64 Mn | 20.76% |
| 3 | Charles River Laboratories International | 14.06 Bn | 13.30 Bn | 363.37 Mn | 11.94% |
| 4 | Icon | 13.44 Bn | 10.55 Bn | 479.29 Mn | 6.68% |
| 5 | Fortrea Holdings | 1.91 Bn | 1.29 Bn | 139.20 Mn | 2.18% |
| 6 | Ginkgo Bioworks Holdings | 665.78 Mn | -96.30 Mn | 18.44 Mn | -290.47% |
| 7 | Evotec SE | 565.34 Mn | -1.01 Bn | - | - |
| 8 | Champions Oncology | 68.06 Mn | 43.71 Mn | 7.70 Mn | -2.69% |
| 9 | MindWalk Holdings | 62.59 Mn | 26.81 Mn | 1.61 Mn | -159.86% |
| 10 | Natural Alternatives International | 10.67 Mn | -22.35 Mn | 383,000.00 | -11.31% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -290.47% |
| Mar 31, 2026 | -366.51% |
| Dec 31, 2025 | -211.86% |
| Sep 30, 2025 | -231.78% |
| Jun 30, 2025 | -148.63% |
| Mar 31, 2025 | -211.80% |
| Dec 31, 2024 | -236.29% |
| Sep 30, 2024 | -61.99% |
| Jun 30, 2024 | -396.66% |
| Mar 31, 2024 | -469.12% |
| Dec 31, 2023 | -512.49% |
| Sep 30, 2023 | -516.68% |
| Jun 30, 2023 | -228.57% |
| Mar 31, 2023 | -267.34% |
| Dec 31, 2022 | -234.89% |
| Sep 30, 2022 | -986.38% |
| Jun 30, 2022 | -447.92% |
| Mar 31, 2022 | -401.04% |
| Dec 31, 2021 | -1,134.55% |
| Sep 30, 2021 | -34.37% |
API Access
Ginkgo Bioworks Holdings Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=DNA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "DNA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=DNA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();