Curis (CRIS) Operating Margin (2010 - 2025)
Curis' Operating Margin came in at 1723.99% for Q4 2025, up 1992.87 percentage points from -268.88% a year earlier and up 1942.00 percentage points from the prior quarter.
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Analysis
Curis (CRIS) Operating Margin (2010 - 2025) Analysis & Trends
For FY2025, Curis' Operating Margin was -60.50%, up 347.84 percentage points from FY2024.
- Operating Margin has increased in each of the last three years, with a five-year change of +169.29 percentage points (FY2020 to FY2025).
- Going back by year, Operating Margin was -408.34% in FY2024 (+73.87 pp), -482.21% in FY2023 (+39.54 pp), -521.75% in FY2022 (-126.73 pp) and -395.01% in FY2021 (-165.22 pp).
- The Q4 2025 figure represents the highest quarterly Operating Margin in data going back to Q2 2010.
- Year-over-year, Operating Margin has increased for seven consecutive quarters, with an average year-over-year change of +340.85 percentage points over the last eight quarters.
- The fastest year-over-year change in Operating Margin over five years came in Q4 2025 (a gain of 1992.87 percentage points), and the weakest in Q1 2022 (a drop of 333.67 percentage points).
- Business Quant data shows CRIS's Operating Margin at -218.01% (Q3 2025), -300.15% (Q2 2025) and -426.76% (Q1 2025) in the three quarters before Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Curis | 1.62 Mn | -32.57 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 1,723.99% |
| Sep 30, 2025 | -218.01% |
| Jun 30, 2025 | -300.15% |
| Mar 31, 2025 | -426.76% |
| Dec 31, 2024 | -268.88% |
| Sep 30, 2024 | -360.53% |
| Jun 30, 2024 | -491.44% |
| Mar 31, 2024 | -597.75% |
| Dec 31, 2023 | -452.49% |
| Sep 30, 2023 | -436.57% |
| Jun 30, 2023 | -552.48% |
| Mar 31, 2023 | -506.18% |
| Dec 31, 2022 | -354.00% |
| Sep 30, 2022 | -446.23% |
| Jun 30, 2022 | -629.38% |
| Mar 31, 2022 | -735.68% |
| Dec 31, 2021 | -400.86% |
| Sep 30, 2021 | -330.64% |
| Jun 30, 2021 | -465.88% |
| Mar 31, 2021 | -402.01% |
API Access
Curis Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CRIS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CRIS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CRIS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();