Curis (CRIS) Operating Margin (2010 - 2025)
Curis (CRIS) reported Operating Margin of 1723.99% for Q4 2025, up 199287.0% on a YoY basis from N/an in Q4 2024, and up 890.78% quarter-over-quarter from 218.01% in Q3 2025.
Curis (CRIS) Operating Margin (2010 - 2025) Analysis & Trends
Curis has reported Operating Margin for 16 years, with the latest figure at 1723.99% in Q4 2025.
- For the quarter ending Q4 2025, Operating Margin rose 199287.0% year-over-year to 1723.99%; the trailing twelve-month figure through Mar 2026 stood at 100.17% (up 27682.0% YoY), and the FY2025 full-year result was 60.5%, up 34784.0% from the prior year.
- Operating Margin for Q4 2025 stood at 1723.99%, up from 218.01% in the prior quarter.
- The five-year high for Operating Margin was 1723.99% in Q4 2025, with the low at 735.68% in Q1 2022.
- Historically, Operating Margin has averaged 332.6% across 5 years, with a median of 431.67% in 2025.
- Annual changes were most pronounced in 2022 — Operating Margin slumped 33367 bps — and 2025, when it soared 199287 bps.
- Curis' Operating Margin stood at 400.86% in 2021, then grew by 12 bps to 354.0% in 2022, then fell by 28 bps to 452.49% in 2023, then jumped by 41 bps to 268.88% in 2024, then surged by 741 bps to 1723.99% in 2025.
- The last three Operating Margin figures came in at 1723.99% (Q4 2025), 218.01% (Q3 2025), and 300.15% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 788,338.31 Bn | 788,338.28 Bn | - | - |
| 2 | Belite Bio | 56,560.00 Bn | 56,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,329.30 Bn | 17,329.30 Bn | - | - |
| 4 | Legend Biotech | 3,341.00 Bn | 3,340.71 Bn | 242.10 Mn | -6.43% |
| 5 | Akari Therapeutics | 1,727.91 Bn | 1,727.91 Bn | - | - |
| 6 | Evaxion A | 1,536.68 Bn | 1,536.67 Bn | - | - |
| 7 | Psyence Biomedical | 238.34 Bn | 238.33 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.42 Bn | 106.17 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 95.45 Bn | 95.45 Bn | - | - |
| 10 | Curis | 8.58 Mn | -6.42 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 1,723.99% |
| Sep 30, 2025 | -218.01% |
| Jun 30, 2025 | -300.15% |
| Mar 31, 2025 | -426.76% |
| Dec 31, 2024 | -268.88% |
| Sep 30, 2024 | -360.53% |
| Jun 30, 2024 | -491.44% |
| Mar 31, 2024 | -597.75% |
| Dec 31, 2023 | -452.49% |
| Sep 30, 2023 | -436.57% |
| Jun 30, 2023 | -552.48% |
| Mar 31, 2023 | -506.18% |
| Dec 31, 2022 | -354.00% |
| Sep 30, 2022 | -446.23% |
| Jun 30, 2022 | -629.38% |
| Mar 31, 2022 | -735.68% |
| Dec 31, 2021 | -400.86% |
| Sep 30, 2021 | -330.64% |
| Jun 30, 2021 | -465.88% |
| Mar 31, 2021 | -402.01% |