Axsome Therapeutics AXSM Insider Ownership

NASDAQ AXSM

$140.97 +7.01 (+5.23%)

At close: Nov 10, 2026 · 4:00 PM EST

Insider Holdings by Owner

151.11K Shares

Roger Jeffs58.37K38.6%

Nick Pizzie42.87K28.4%

Mark Coleman30.39K20.1%

Mark E Saad11.43K7.6%

Herriot Tabuteau7.23K4.8%

Other insiders (1)8290.5%

Insider Ownership Statistics

as of 30 Sep, 2026

Insider Ownership

1.06%

■0% pp QoQ

Shares Held by Insiders

555.21K

filed for Sep 2026

■0.00% QoQ

Shares Outstanding

52.30Mn

52,299,889 shares

Direct Holdings

151.11K

Indirect: 404.10K

Net Open-Market Trades

-109.33K

net sold · -$24.56Mn in Sep 2026

Insiders Holding Shares

with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Open-Market Insider Trades

Bought Sold

Latest quarter —

Net over range —

Net-buying quarters —

Insider Ownership Summary

Updated Nov 5, 2026

Over the trailing 12 months, AXSM insiders sold $115.44 million worth of shares (614.63K shares) in open-market trades, with no open-market purchases.

Behind Axsome Therapeutics' open-market sales in the past 12 months were 8 insiders, and no insider bought.
The largest open-market sales of AXSM in the past 12 months were by Herriot Tabuteau (Chief Executive Officer), totaling $78.92 million (422.57K shares), most recently on August 6, 2026.
The latest open-market trade in AXSM stock by an insider was a sale of 10K shares for $2.09 million by Mark L. Jacobson (Chief Operating Officer) on September 3, 2026.
Outside the open market, Axsome Therapeutics insiders acquired 595.63K shares through option exercises and conversions over the past 12 months.
According to Business Quant data, insiders at Axsome Therapeutics reported 554.97K shares in total in their latest Form 4 filings, down 0.04% from 555.21K shares at the end of Q2 2026 and down 2.51% from 569.24K shares at the end of Q3 2025.
By type of ownership, AXSM insiders hold 27.23% of their shares directly (151.11K shares) and 72.77% indirectly (403.86K shares).
AXSM's insider total is spread across 6 insiders who have filed a Form 4 in the past two years.
AXSM's three largest insider shareholders, per their latest Form 4 filings, are Mark Coleman (Director, 434.25K shares), Roger Jeffs (Director, 58.37K shares) and Nick Pizzie (Chief Financial Officer, 42.87K shares).
Of the shares held by AXSM insiders, 78.25% belong to Mark Coleman.
Institutional investors held 72.73% of Axsome Therapeutics stock at the end of Q2 2026, while the latest Form 4 filings of its insiders account for about 1.06%; other investors, including the public, hold roughly 26.21%.
A total of 39 Form 4 filings with transactions in Axsome Therapeutics stock were made over the past 12 months, by 9 insiders.
The insider holdings and trades above for Axsome Therapeutics reflect Form 4 filings through September 3, 2026.

Form 4 Holdings

Insiders Holding AXSM

Insiders 6

Shares held 151.11K

Of outstanding 0.289%

#	Insider	Position	Direct	Total	Share of Insiders	Last Filed
1	Roger Jeffs	Director	58,367	58,367	38.6%	11 Jun, 2026
2	Nick Pizzie	Chief Financial Officer	42,867	42,867	28.4%	09 Jun, 2026
3	Mark Coleman	Director	30,389	30,389	20.1%	10 Jun, 2026
4	Mark E Saad	Director	11,431	11,431	7.6%	10 Jun, 2026
5	Herriot Tabuteau	Chief Executive Officer	7,229	7,229	4.8%	07 Aug, 2026
6	Susan Mahony	Director	829	829	0.5%	10 Jun, 2026

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

418 Insider Transactions

Source SEC Form 4

Latest quarter Sep 2026

Date	Insider	Position	Transaction	Shares	Price	Value	Shares Held After	Ownership
03 Sep, 2026	Mark L. Jacobson	Chief Operating Officer	Acquired M	10,000	$12.95	$129.50K	10,000	Direct
03 Sep, 2026	Mark L. Jacobson	Chief Operating Officer	Disposed S	10,000	$208.65	$2.09Mn	0	Direct
03 Sep, 2026	Mark L. Jacobson	Chief Operating Officer	Disposed M	10,000	$0.00	$0	104,954	Direct
05 Aug, 2026	Herriot Tabuteau	Chief Executive Officer	Acquired M	45,004	$4.95	$222.77K	52,233	Direct
05 Aug, 2026	Herriot Tabuteau	Chief Executive Officer	Disposed S	45,004	$212.01	$9.54Mn	7,229	Direct
06 Aug, 2026	Herriot Tabuteau	Chief Executive Officer	Acquired M	4,660	$4.95	$23.07K	11,889	Direct
06 Aug, 2026	Herriot Tabuteau	Chief Executive Officer	Disposed S	4,660	$213.95	$997.01K	7,229	Direct
05 Aug, 2026	Herriot Tabuteau	Chief Executive Officer	Disposed M	45,004	$0.00	$0	4,660	Direct
06 Aug, 2026	Herriot Tabuteau	Chief Executive Officer	Disposed M	4,660	$0.00	$0	0	Direct
01 Jul, 2026	Herriot Tabuteau	Chief Executive Officer	Acquired M	49,666	$4.95	$245.85K	56,895	Direct
01 Jul, 2026	Herriot Tabuteau	Chief Executive Officer	Disposed S	49,666	$240.25	$11.93Mn	7,229	Direct
01 Jul, 2026	Herriot Tabuteau	Chief Executive Officer	Disposed M	49,666	$0.00	$0	49,664	Direct
10 Jun, 2026	Roger Jeffs	Director	Disposed S	286	$246.18	$70.41K	58,653	Direct
11 Jun, 2026	Roger Jeffs	Director	Disposed S	286	$249.12	$71.25K	58,367	Direct
08 Jun, 2026	Susan Mahony	Director	Acquired M	1,429	—	—	1,429	Direct
08 Jun, 2026	Roger Jeffs	Director	Acquired M	1,429	—	—	58,939	Direct
08 Jun, 2026	Mark E Saad	Director	Acquired M	1,429	—	—	11,431	Direct
08 Jun, 2026	Mark Coleman	Director	Acquired M	1,429	—	—	31,032	Direct
08 Jun, 2026	Roger Jeffs	Director	Disposed M	1,429	$0.00	$0	0	Direct
09 Jun, 2026	Susan Mahony	Director	Disposed S	300	$237.21	$71.16K	1,129	Direct

Showing 1 to 20 of 418 transactions