Arrowhead Pharmaceuticals (ARWR) Operating Margin (2010 - 2026)
Arrowhead Pharmaceuticals' (ARWR) quarterly Operating Margin came in at 191.57% in Q1 2026, down 26181.0% YoY from N/an in Q1 2025, and down 1339.47% on a QoQ basis from 15.46% in Q4 2025.
Analysis
Arrowhead Pharmaceuticals (ARWR) Operating Margin (2010 - 2026) Analysis & Trends
Arrowhead Pharmaceuticals (ARWR) has 17 years of Operating Margin data on file, last reported at 191.57% in Q1 2026.
- Quarterly Operating Margin fell 26181.0% year-over-year to 191.57% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 35.67% (down 1393.0% YoY) and the FY2025 annual result came in at 11.86%, up 1693892.0% from the prior year.
- Operating Margin eased to 191.57% in Q1 2026, from 15.46% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 70.24% in Q1 2025 to a low of 6456.48% in Q4 2024.
- A 5-year average of 914.72% and a median of 208.26% in 2022 frame the typical range for Operating Margin.
- Annual changes were most pronounced in 2023 — Operating Margin tumbled 377789 bps — and 2025, when it soared 647194 bps.
- Tracing ARWR's Operating Margin over 5 years: stood at 67.36% in 2022, then tumbled by 5608 bps to 3845.25% in 2023, then slumped by 68 bps to 6456.48% in 2024, then jumped by 100 bps to 15.46% in 2025, then plunged by 1339 bps to 191.57% in 2026.
- The last three Operating Margin figures came in at 191.57% (Q1 2026), 15.46% (Q4 2025), and 17.2% (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -562.07% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 19.06% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 17.93% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 19.75% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -0.36% |
| 10 | Arrowhead Pharmaceuticals | 12.40 Bn | 10.80 Bn | - | -226.03% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -226.03% |
| Mar 31, 2026 | -191.57% |
| Dec 31, 2025 | 15.46% |
| Sep 30, 2025 | 17.20% |
| Jun 30, 2025 | -596.21% |
| Mar 31, 2025 | 70.24% |
| Dec 31, 2024 | -6,456.48% |
| Dec 31, 2023 | -3,845.25% |
| Sep 30, 2023 | -672.98% |
| Jun 30, 2023 | -648.99% |
| Mar 31, 2023 | 32.93% |
| Dec 31, 2022 | -67.36% |
| Sep 30, 2022 | -265.49% |
| Jun 30, 2022 | -224.94% |
| Mar 31, 2022 | 27.37% |
| Dec 31, 2021 | -230.77% |
| Sep 30, 2021 | -169.48% |
| Jun 30, 2021 | -69.44% |
| Mar 31, 2021 | -86.04% |
| Dec 31, 2020 | -112.91% |