Arrowhead Pharmaceuticals ARWR
NASDAQ ARWR
$86.36 -0.13 (-0.15%)
As of: Sep 4, 2026 · 3:59 PM EDT

Arrowhead Pharmaceuticals (ARWR) Operating Income (2010 - 2026)

Arrowhead Pharmaceuticals' (ARWR) quarterly Operating Income came in at -$141.3 million in Q1 2026, down 137.06% YoY from $381.2 million in Q1 2025, and down 446.15% on a QoQ basis from $40.8 million in Q4 2025.

Analysis

Arrowhead Pharmaceuticals (ARWR) Operating Income (2010 - 2026) Analysis & Trends

Arrowhead Pharmaceuticals (ARWR) has 17 years of Operating Income data on file, last reported at -$141.3 million in Q1 2026.

  • Quarterly Operating Income fell 137.06% year-over-year to -$141.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$221.9 million (down 87.17% YoY) and the FY2025 annual result came in at $98.3 million, up 116.36% from the prior year.
  • Operating Income eased to -$141.3 million in Q1 2026, from $40.8 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $381.2 million in Q1 2025 to a low of -$176.1 million in Q2 2024.
  • A 5-year average of -$54.3 million and a median of -$102.7 million in 2023 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2024 — Operating Income sank 362.0% — and 2025, when it soared 402.08%.
  • Tracing ARWR's Operating Income over 5 years: stood at -$42.1 million in 2022, then tumbled by 224.07% to -$136.5 million in 2023, then fell by 18.21% to -$161.4 million in 2024, then jumped by 125.28% to $40.8 million in 2025, then plunged by 446.15% to -$141.3 million in 2026.
  • The last three Operating Income figures came in at -$141.3 million (Q1 2026), $40.8 million (Q4 2025), and $44.1 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -505.13 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 133.12 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -1.55 Mn
10 Arrowhead Pharmaceuticals 12.40 Bn 10.80 Bn - -170.09 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -170.09 Mn
Mar 31, 2026 -141.26 Mn
Dec 31, 2025 40.81 Mn
Sep 30, 2025 44.11 Mn
Jun 30, 2025 -165.55 Mn
Mar 31, 2025 381.20 Mn
Dec 31, 2024 -161.41 Mn
Sep 30, 2024 -162.20 Mn
Jun 30, 2024 -176.14 Mn
Mar 31, 2024 -126.19 Mn
Dec 31, 2023 -136.55 Mn
Sep 30, 2023 -108.33 Mn
Jun 30, 2023 -102.70 Mn
Mar 31, 2023 48.17 Mn
Dec 31, 2022 -42.13 Mn
Sep 30, 2022 -83.83 Mn
Jun 30, 2022 -72.91 Mn
Mar 31, 2022 41.55 Mn
Dec 31, 2021 -63.32 Mn
Sep 30, 2021 -64.88 Mn