Arrowhead Pharmaceuticals (ARWR) Operating Margin (2010 - 2026)
Arrowhead Pharmaceuticals (ARWR) recorded Operating Margin of -226.03% in fiscal Q3 2026 (quarter ended Jun 30, 2026), up 370.18 percentage points from -596.21% a year earlier but down 34.46 percentage points from the prior quarter.
Arrowhead Pharmaceuticals (ARWR) Operating Margin (2010 - 2026) Analysis & Trends
On a TTM basis, Arrowhead Pharmaceuticals' Operating Margin came in at -33.82% as of Jun 30, 2026, down 14.98 percentage points year-over-year; for FY2025 (ended Sep 30, 2025), it came in at 11.86%, up 16938.92 percentage points from FY2024.
- Annual Operating Margin has a five-year change of +117.73 percentage points (FY2020 to FY2025).
- Across earlier fiscal years, Operating Margin came in at -16927.06% in FY2024 (-16841.91 pp), -85.16% in FY2023 (-11.77 pp), -73.39% in FY2022 (+34.38 pp) and -107.77% in FY2021 (-1.90 pp).
- Quarterly Operating Margin has ranged from -6456.48% in fiscal Q1 2025 to 70.24% in fiscal Q2 2025 over the past five years.
- On a year-over-year basis, Operating Margin rose in two of the last four quarters, with an average year-over-year change of +992.27 percentage points.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 6471.94 percentage points in fiscal Q1 2026, against a drop of 3777.89 percentage points in fiscal Q1 2024 at the low end.
- Per Business Quant, the preceding three fiscal quarters came in at -191.57% (Q2 2026), 15.46% (Q1 2026) and 17.20% (Q4 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Arrowhead Pharmaceuticals | 9.24 Bn | 4.02 Bn | - | -226.03% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -226.03% |
| Mar 31, 2026 | -191.57% |
| Dec 31, 2025 | 15.46% |
| Sep 30, 2025 | 17.20% |
| Jun 30, 2025 | -596.21% |
| Mar 31, 2025 | 70.24% |
| Dec 31, 2024 | -6,456.48% |
| Dec 31, 2023 | -3,845.25% |
| Sep 30, 2023 | -672.98% |
| Jun 30, 2023 | -648.99% |
| Mar 31, 2023 | 32.93% |
| Dec 31, 2022 | -67.36% |
| Sep 30, 2022 | -265.49% |
| Jun 30, 2022 | -224.94% |
| Mar 31, 2022 | 27.37% |
| Dec 31, 2021 | -230.77% |
| Sep 30, 2021 | -169.48% |
| Jun 30, 2021 | -69.44% |
| Mar 31, 2021 | -86.04% |
| Dec 31, 2020 | -112.91% |
Arrowhead Pharmaceuticals Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ARWR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ARWR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ARWR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();