Arrowhead Pharmaceuticals (ARWR) EBITDA Margin (2010 - 2026)

Arrowhead Pharmaceuticals' (ARWR) quarterly EBITDA Margin came in at 191.57% in Q1 2026, down 26181.0% YoY from N/an in Q1 2025, and down 1339.47% on a QoQ basis from 15.46% in Q4 2025.

Arrowhead Pharmaceuticals (ARWR) EBITDA Margin (2010 - 2026) Analysis & Trends

Arrowhead Pharmaceuticals (ARWR) has 17 years of EBITDA Margin data on file, last reported at 191.57% in Q1 2026.

  • Quarterly EBITDA Margin fell 26181.0% year-over-year to 191.57% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 35.67% (down 1393.0% YoY) and the FY2025 annual result came in at 11.86%, up 1693892.0% from the prior year.
  • EBITDA Margin eased to 191.57% in Q1 2026, from 15.46% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 70.24% in Q1 2025 to a low of 6456.48% in Q4 2024.
  • A 5-year average of 914.72% and a median of 208.26% in 2022 frame the typical range for EBITDA Margin.
  • Annual changes were most pronounced in 2023 — EBITDA Margin tumbled 377789 bps — and 2025, when it soared 647194 bps.
  • Tracing ARWR's EBITDA Margin over 5 years: stood at 67.36% in 2022, then tumbled by 5608 bps to 3845.25% in 2023, then slumped by 68 bps to 6456.48% in 2024, then jumped by 100 bps to 15.46% in 2025, then plunged by 1339 bps to 191.57% in 2026.
  • The last three EBITDA Margin figures came in at 191.57% (Q1 2026), 15.46% (Q4 2025), and 17.2% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.15%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 31.68%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 19.06%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -77,569,866.34%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.75%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 17.93%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -0.36%
10 Arrowhead Pharmaceuticals 12.23 Bn 10.63 Bn - -226.03%

Historic Data

Download Data
DateValue
Jun 30, 2026 -226.03%
Mar 31, 2026 -191.57%
Dec 31, 2025 15.46%
Sep 30, 2025 17.20%
Jun 30, 2025 -596.21%
Mar 31, 2025 70.24%
Dec 31, 2024 -6,456.48%
Dec 31, 2023 -3,845.25%
Sep 30, 2023 -672.98%
Jun 30, 2023 -648.99%
Mar 31, 2023 32.93%
Dec 31, 2022 -67.36%
Sep 30, 2022 -265.49%
Jun 30, 2022 -224.94%
Mar 31, 2022 27.37%
Dec 31, 2021 -230.77%
Sep 30, 2021 -169.48%
Jun 30, 2021 -69.44%
Mar 31, 2021 -86.04%
Dec 31, 2020 -112.91%