According to recent filings covering the 90 days ending December 12, 2025, the three most significant insider holders at Arrowhead Pharmaceuticals are Chief Executive Officer Christopher Richard Anzalone (3.92Mn shares), COO And General Counsel Patrick O'Brien (527.20K shares), Chief Financial Officer Kenneth Allen Myszkowski (455.43K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Christopher Richard Anzalone | Chief Executive Officer | 3,921,255 | 11 Apr, 2025 |
| Patrick O'Brien | COO And General Counsel | 527,201 | 07 Jan, 2025 |
| Kenneth Allen Myszkowski | Chief Financial Officer | 455,433 | 07 Jan, 2025 |
| James C Hamilton | Chief Medical Officer | 212,122 | 03 Oct, 2025 |
| Martin Javier San | Chief Medical Officer | 198,497 | 08 Jan, 2024 |
| Douglas B Given | 137,167 | 18 Dec, 2024 | |
| Tracie Oliver | Chief Commercial Officer | 127,107 | 03 Jul, 2024 |
| Michael S Perry | 115,240 | 09 Dec, 2025 | |
| James Hassard | Chief Commercial Officer | 105,750 | 24 Jun, 2021 |
| Mauro Ferrari | 68,764 | 01 Dec, 2025 | |
| William D. Waddill | 57,111 | 20 Dec, 2024 | |
| Hongbo Lu | 47,163 | 20 Dec, 2024 | |
| Douglas S Ingram | 38,396 | 07 Feb, 2025 | |
| Victoria Vakiener | 37,944 | 20 Dec, 2024 | |
| Adeoye Y Olukotun | 35,781 | 27 Jan, 2025 | |
| Backer Marianne De | 31,267 | 11 Jan, 2023 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 05 Dec, 2025 | Michael S Perry | Common Stock | D | 16,250 | $61.03 | 115,240 | D | S |
| 28 Nov, 2025 | Mauro Ferrari | Common Stock | D | 8,750 | $56.39 | 68,764 | D | S |
| 01 Oct, 2025 | James C Hamilton | Common Stock | D | 20,000 | $35.00 | 212,122 | D | S |
| 12 Sep, 2025 | James C Hamilton | Common Stock | D | 15,000 | $30.00 | 232,122 | D | S |
| 02 Sep, 2025 | James C Hamilton | Common Stock | D | 15,000 | $25.00 | 247,122 | D | S |
| 13 Aug, 2025 | James C Hamilton | Common Stock | D | 611 | $20.00 | 271,511 | D | S |
| 15 Aug, 2025 | James C Hamilton | Common Stock | D | 9,389 | $20.00 | 262,122 | D | S |
| 09 Apr, 2025 | Christopher Richard Anzalone | - | - | 4,027,072 | D | |||
| 09 Apr, 2025 | Christopher Richard Anzalone | Common Stock | D | 35,305 | $9.93 | 4,027,072 | D | S |
| 09 Apr, 2025 | Christopher Richard Anzalone | - | - | 4,023,672 | D | |||
| 09 Apr, 2025 | Christopher Richard Anzalone | Common Stock | D | 3,400 | $10.75 | 4,023,672 | D | S |
| 09 Apr, 2025 | Christopher Richard Anzalone | - | - | 4,022,055 | D | |||
| 09 Apr, 2025 | Christopher Richard Anzalone | Common Stock | D | 1,617 | $11.76 | 4,022,055 | D | S |
| 10 Apr, 2025 | Christopher Richard Anzalone | - | - | 3,972,055 | D | |||
| 10 Apr, 2025 | Christopher Richard Anzalone | Common Stock | D | 50,000 | $10.87 | 3,972,055 | D | S |
| 11 Apr, 2025 | Christopher Richard Anzalone | - | - | 3,921,255 | D | |||
| 11 Apr, 2025 | Christopher Richard Anzalone | Common Stock | D | 50,800 | $11.49 | 3,921,255 | D | S |
| 13 Mar, 2025 | Christopher Richard Anzalone | Common Stock | A | 340,000 | $0.00 | 4,113,802 | D | A |
| 13 Mar, 2025 | Christopher Richard Anzalone | Common Stock | D | 51,425 | $15.07 | 4,062,377 | D | S |
| 03 Mar, 2025 | Christopher Richard Anzalone | Common Stock | A | 166,667 | $7.75 | 3,940,469 | D | M |