Arrowhead Pharmaceuticals, Inc. (ARWR) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

7,099,032Shares held by institutions

$409,401,175Value of institutional holdings

75.85%Institutional ownership %

-0.33%Shares Changed QoQ

278No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) has 390 institutional investors with active 13F positions as of December 2025.

Their combined ownership stood at 82.3% of outstanding shares in December 2025, down from 83.5% in September 2025.
Their total shares held in ARWR increased 3.94% quarter over quarter, and separately, investors owning Arrowhead Pharmaceuticals increased 45.52% from a year ago.
Activity in ARWR broke down as 247 buyers, 109 sellers, and 34 unchanged among 390 total holders.
Combined, these investors held 115.83Mn shares in ARWR for December 2025, up by 4.39Mn shares quarter on quarter, and up 13.65Mn shares year over year.
BlackRock, Inc. leads ownership in ARWR with 21.32Mn shares as of December 31, 2025, equal to 15.15% of outstanding shares.
Top purchasers of ARWR stock for the quarter ending December 2025 included NORGES BANK (1.7Mn), FRED ALGER MANAGEMENT, LLC (1.53Mn), BlackRock, Inc. (1.09Mn), Vestal Point Capital, LP (900.0K), DEERFIELD MANAGEMENT COMPANY, L.P. (839.95K).
Top sellers of ARWR stock for the quarter ending December 2025 included Slate Path Capital LP (2.46Mn), MARSHALL WACE, LLP (1.31Mn), Siren, L.L.C. (1.17Mn), Jpmorgan Chase & Co (939.52K), Bank Of America Corp /De/ (899.34K).
According to Business Quant data, leading holders of ARWR for December 2025 are BlackRock, Inc. (21.32Mn), VANGUARD GROUP INC (15.29Mn), Avoro Capital Advisors LLC (10.62Mn), FMR LLC (6.52Mn), State Street Corp (6.4Mn), GEODE CAPITAL MANAGEMENT, LLC (3.26Mn), Slate Path Capital LP (2.52Mn), BAKER BROS. ADVISORS LP (2.18Mn), ARROWSTREET CAPITAL, LIMITED PARTNERSHIP (2.09Mn), FRED ALGER MANAGEMENT, LLC (1.83Mn).

390 Institutional Holders

7,099,032 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	1,093,757	5.41%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	-742,749	-4.63%	$0.00
Avoro Capital Advisors LLC	31 Dec, 2025	10,350,000	94.95%	$0.00
FMR LLC	31 Dec, 2025	760,578	13.20%	$0.00
Siren, L.L.C.	31 Dec, 2025	-1,169,404	-43.80%	$0.00
Barclays Plc	31 Dec, 2025	-305,016	-48.66%	$0.00
State Street Corp	31 Dec, 2025	6,466	0.10%	$0.00
Pictet Asset Management Holding SA	31 Dec, 2025	737,713	253.49%	$0.00
World Investment Advisors	31 Dec, 2025	8,197	59.50%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	133,921	4.28%	$0.00
UBS Group AG	31 Dec, 2025	69,104	7.53%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	224	25.17%	$0.00
Slate Path Capital LP	31 Dec, 2025	-2,458,500	-49.35%	$0.00
Vestal Point Capital, LP	31 Dec, 2025	900,000	0.00%	$0.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	504,883	30.22%	$0.00
Western Financial Corp/CA	31 Dec, 2025	0	0.00%	$0.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	31 Dec, 2025	6,264	0.30%	$0.00
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	31 Dec, 2025	470,000	0.00%	$0.00
FRED ALGER MANAGEMENT, LLC	31 Dec, 2025	1,526,164	497.39%	$0.00
Woodline Partners LP	31 Dec, 2025	-599,974	-59.99%	$0.00

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