Amylyx Pharmaceuticals AMLX
NASDAQ AMLX
$38.87 +0.27 (+0.70%)
At close: Aug 20, 2026 · 9:59 AM UTC

Amylyx Pharmaceuticals (AMLX) Operating Margin (2021 - 2024)

Amylyx Pharmaceuticals (AMLX) posted quarterly Operating Margin of 6392.14% for Q4 2024, up 639036.0% year-over-year from N/an in Q1 2024, and up 135.15% quarter-over-quarter from 18187.74% in Q3 2024.

Amylyx Pharmaceuticals (AMLX) Operating Margin (2021 - 2024) Analysis & Trends

Amylyx Pharmaceuticals' Operating Margin history runs 4 years deep, the most recent figure standing at 6392.14% for Q4 2024.

  • In Q4 2024, Operating Margin rose 639036.0% year-over-year to 6392.14%; the TTM figure through Sep 2025 stood at 24739.15% (up 2487623.0% YoY), while the FY2024 annual figure was 360.1%, down 37029.0% from the prior year.
  • Operating Margin for Q4 2024 stood at 6392.14%, up from 18187.74% in the prior quarter.
  • The five-year high for Operating Margin was 6392.14% in Q4 2024, with the low at 18187.74% in Q3 2024.
  • The 4-year median for Operating Margin is 137.78% (2024), against an average of 3949.77%.
  • The sharpest annual moves came in 2023 and 2024: Operating Margin jumped 1586779 bps in 2023, then tumbled 1820597 bps in 2024.
  • Amylyx Pharmaceuticals' Operating Margin stood at 8041.4% in 2021, then soared by 97 bps to 203.76% in 2022, then surged by 101 bps to 1.78% in 2023, then surged by 358339 bps to 6392.14% in 2024.
  • Business Quant data shows AMLX's Operating Margin at 6392.14% in Q4 2024, 18187.74% in Q3 2024, and 7457.09% in Q2 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Haleon 43.71 Bn 42.75 Bn - -
2 Teva Pharmaceutical Industries 43.11 Bn 39.45 Bn 2.15 Bn -5.58%
3 Zoetis 31.62 Bn 29.94 Bn 1.05 Bn 33.91%
4 Takeda Pharmaceutical 28.72 Bn 22.92 Bn 5.10 Bn 16.51%
5 United Therapeutics 22.33 Bn 19.67 Bn 683.80 Mn 42.23%
6 Viatris 18.83 Bn 17.95 Bn 1.46 Bn 0.17%
7 Neurocrine Biosciences 15.62 Bn 15.23 Bn 935.80 Mn 15.80%
8 Elanco Animal Health 12.10 Bn 11.57 Bn 798.00 Mn 18.13%
9 Dr Reddys Laboratories 10.11 Bn 9.94 Bn - -
10 Amylyx Pharmaceuticals 4.28 Bn 4.28 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2024 6,392.14%
Sep 30, 2024 -18,187.74%
Jun 30, 2024 -7,457.09%
Mar 31, 2024 -137.78%
Dec 31, 2023 1.78%
Sep 30, 2023 18.23%
Jun 30, 2023 20.57%
Mar 31, 2023 -2.87%
Dec 31, 2022 -203.76%
Sep 30, 2022 -15,849.57%
Sep 30, 2021 -8,041.40%