Amylyx Pharmaceuticals AMLX
NASDAQ AMLX
$33.19 -0.69 (-2.04%)
As of: Sep 9, 2026 · 12:04 PM EDT

Amylyx Pharmaceuticals (AMLX) Operating Margin (2021 - 2024)

Amylyx Pharmaceuticals (AMLX) posted Operating Margin of 6392.14% for Q4 2024, up 135.15% on a QoQ basis from 18187.74% in Q3 2024, and up 639036.0% year-over-year from N/an in Q1 2024.

Analysis

Amylyx Pharmaceuticals (AMLX) Operating Margin (2021 - 2024) Analysis & Trends

Amylyx Pharmaceuticals has reported Operating Margin for 4 years, with the latest figure at 6392.14% in Q4 2024.

  • On a quarterly basis, Operating Margin rose 639036.0% year-over-year to 6392.14% in Q4 2024; TTM through Sep 2025 was 24739.15%, a 2487623.0% increase from a year earlier, with the FY2024 full-year figure at 360.1%, down 37029.0% from the prior year.
  • Operating Margin was 6392.14% for Q4 2024 at Amylyx Pharmaceuticals, up from 18187.74% in the prior quarter.
  • The five-year high for Operating Margin was 6392.14% in Q4 2024, with the low at 18187.74% in Q3 2024.
  • Average Operating Margin over 4 years is 3949.77%, with a median of 137.78% recorded in 2024.
  • The sharpest annual moves came in 2023 and 2024: Operating Margin soared 1586779 bps in 2023, then tumbled 1820597 bps in 2024.
  • Over 4 years, Operating Margin stood at 8041.4% in 2021, then surged by 97 bps to 203.76% in 2022, then jumped by 101 bps to 1.78% in 2023, then jumped by 358339 bps to 6392.14% in 2024.
  • The last three Operating Margin figures came in at 6392.14% (Q4 2024), 18187.74% (Q3 2024), and 7457.09% (Q2 2024), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Amgen 211.88 Bn 197.89 Bn 7.24 Bn 34.95%
2 Gilead Sciences 181.55 Bn 178.37 Bn 6.22 Bn -133.21%
3 Vertex Pharmaceuticals 132.31 Bn 124.45 Bn 2.84 Bn 37.40%
4 Regeneron Pharmaceuticals 82.51 Bn 74.52 Bn 3.93 Bn 30.15%
5 Argenx Se 61.54 Bn 56.36 Bn 1.37 Bn 32.54%
6 Moderna 54.69 Bn 49.55 Bn 52.00 Mn -562.07%
7 Alnylam Pharmaceuticals 34.07 Bn 30.76 Bn 992.69 Mn 17.93%
8 Biogen 31.41 Bn 30.12 Bn 1.96 Bn -23.56%
9 Roivant Sciences 30.10 Bn 30.10 Bn 1.16 Mn -25,380.93%
10 Amylyx Pharmaceuticals 3.69 Bn 3.69 Bn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2024 6,392.14%
Sep 30, 2024 -18,187.74%
Jun 30, 2024 -7,457.09%
Mar 31, 2024 -137.78%
Dec 31, 2023 1.78%
Sep 30, 2023 18.23%
Jun 30, 2023 20.57%
Mar 31, 2023 -2.87%
Dec 31, 2022 -203.76%
Sep 30, 2022 -15,849.57%
Sep 30, 2021 -8,041.40%