Amylyx Pharmaceuticals (AMLX) Operating Margin (2021 - 2024)

Amylyx Pharmaceuticals (AMLX) recorded quarterly Operating Margin of 31673.38% in Q4 2024, down 74.15% quarter-over-quarter from 18187.74% in Q3 2024, and down 3167593.0% on a YoY basis from N/an in Q1 2024.

Amylyx Pharmaceuticals (AMLX) Operating Margin (2021 - 2024) Analysis & Trends

Amylyx Pharmaceuticals' Operating Margin history runs 4 years deep, the most recent figure standing at 31673.38% for Q4 2024.

  • In Q4 2024, Operating Margin fell 3167593.0% year-over-year to 31673.38%; the TTM figure through Sep 2025 stood at 14126.47% (down 1396257.0% YoY), while the FY2024 annual figure was 72.62%, down 8281.0% from the prior year.
  • Operating Margin was 31673.38% for Q4 2024 at Amylyx Pharmaceuticals, down from 18187.74% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 18.63% in Q2 2023 to a low of 31673.38% in Q4 2024.
  • Historically, Operating Margin has averaged 6878.42% across 4 years, with a median of 205.66% in 2022.
  • The sharpest annual moves came in 2023 and 2024: Operating Margin surged 1001476 bps in 2023, then sank 3167593 bps in 2024.
  • A 4-year view of Operating Margin shows it stood at 8041.4% in 2021, then soared by 97 bps to 205.66% in 2022, then jumped by 101 bps to 2.55% in 2023, then sank by 1244173 bps to 31673.38% in 2024.
  • The last three Operating Margin figures came in at 31673.38% (Q4 2024), 18187.74% (Q3 2024), and 7457.09% (Q2 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Teva Pharmaceutical Industries 39.72 Bn 35.98 Bn 1.97 Bn 16.37%
2 Zoetis 34.61 Bn 32.67 Bn 1.62 Bn 36.83%
3 United Therapeutics 24.07 Bn 21.91 Bn 648.10 Mn 41.69%
4 Aurora Cannabis 16.98 Bn 16.91 Bn 33.43 Mn 20.77%
5 Neurocrine Biosciences 16.64 Bn 15.32 Bn 800.70 Mn 23.74%
6 Elanco Animal Health 12.19 Bn 11.76 Bn 785.00 Mn 22.39%
7 Alkermes 7.37 Bn 6.86 Bn -116.06 Mn -122.23%
8 Hims & Hers Health 6.62 Bn 5.87 Bn 396.79 Mn -12.88%
9 Lantheus Holdings 6.47 Bn 5.97 Bn 230.92 Mn 21.55%
10 Amylyx Pharmaceuticals 1.51 Bn 1.51 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2024 -31,673.38%
Sep 30, 2024 -18,187.74%
Jun 30, 2024 -7,457.09%
Mar 31, 2024 -137.78%
Dec 31, 2023 2.55%
Sep 30, 2023 18.23%
Jun 30, 2023 18.63%
Mar 31, 2023 -2.43%
Dec 31, 2022 -205.66%
Sep 30, 2022 -9,996.53%
Sep 30, 2021 -8,041.40%