Alector (ALEC) Operating Margin (2018 - 2026)
Alector's Operating Margin was -734.73% in Q2 2026, down 301.18 percentage points from -433.55% a year earlier but up 1647.58 percentage points from the prior quarter.
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Analysis
Alector (ALEC) Operating Margin (2018 - 2026) Analysis & Trends
On a trailing twelve-month basis, Alector's Operating Margin was -912.40% through Jun 30, 2026, down 746.60 percentage points year-over-year; for FY2025, it was -741.30%, down 597.11 percentage points from FY2024.
- Operating Margin shows a five-year change of +183.78 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -144.19% in FY2024 (+12.14 pp), -156.33% in FY2023 (-53.18 pp), -103.16% in FY2022 (-85.12 pp) and -18.04% in FY2021 (+907.04 pp).
- Quarterly Operating Margin has moved between -2382.31% (Q1 2026) and 69.25% (Q3 2021) over five years.
- Compared with a year earlier, Operating Margin has declined for six straight quarters, with an average year-over-year change of -432.49 percentage points over the last eight quarters.
- The best year-over-year quarter for Operating Margin over five years was Q1 2022 (a gain of 1100.37 percentage points); the worst was Q1 2026 (a drop of 1165.79 percentage points).
- Per Business Quant data, ALEC's Operating Margin in the three quarters before Q2 2026 was -2382.31% (Q1 2026), -634.38% (Q4 2025) and -1153.62% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Alector | 214.38 Mn | -712.06 Mn | - | -734.73% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -734.73% |
| Mar 31, 2026 | -2,382.31% |
| Dec 31, 2025 | -634.38% |
| Sep 30, 2025 | -1,153.62% |
| Jun 30, 2025 | -433.55% |
| Mar 31, 2025 | -1,216.52% |
| Dec 31, 2024 | -13.36% |
| Sep 30, 2024 | -315.70% |
| Jun 30, 2024 | -302.37% |
| Mar 31, 2024 | -275.01% |
| Dec 31, 2023 | -312.40% |
| Sep 30, 2023 | -555.31% |
| Jun 30, 2023 | -6.38% |
| Mar 31, 2023 | -302.83% |
| Dec 31, 2022 | -383.92% |
| Sep 30, 2022 | -321.49% |
| Jun 30, 2022 | 11.87% |
| Mar 31, 2022 | -180.29% |
| Dec 31, 2021 | -398.23% |
| Sep 30, 2021 | 69.25% |
API Access
Alector Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ALEC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ALEC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ALEC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();