Alector (ALEC) Operating Margin (2018 - 2026)
Alector (ALEC) reported Operating Margin of 2382.31% for Q1 2026, down 116579.0% year-over-year from N/an in Q1 2025, and down 271.85% quarter-over-quarter from 1386.26% in Q4 2025.
Alector (ALEC) Operating Margin (2018 - 2026) Analysis & Trends
Alector (ALEC) has 9 years of Operating Margin data on file, last reported at 2382.31% in Q1 2026.
- Operating Margin for Q1 2026 came in at 2382.31%, down 116579.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 55.41% (up 10985.0% YoY), and the FY2025 annual result was 142.46%, up 174.0% from the prior year.
- Operating Margin slipped to 2382.31% in Q1 2026 per ALEC's latest filing, from 1386.26% in the prior quarter.
- Over five years, Operating Margin peaked at 1386.26% in Q4 2025 and troughed at 2382.31% in Q1 2026.
- A 5-year average of 348.85% and a median of 302.83% in 2023 frame the typical range for Operating Margin.
- The sharpest annual moves came in 2025 and 2026: Operating Margin surged 139962 bps in 2025, then slumped 116579 bps in 2026.
- A 5-year view of Operating Margin shows it stood at 383.92% in 2022, then jumped by 234 bps to 514.15% in 2023, then sank by 103 bps to 13.36% in 2024, then surged by 10473 bps to 1386.26% in 2025, then sank by 272 bps to 2382.31% in 2026.
- Business Quant data shows ALEC's Operating Margin at 2382.31% in Q1 2026, 1386.26% in Q4 2025, and 1153.62% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Alector | 193.53 Mn | -12.98 Mn | - | -2,382.31% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -2,382.31% |
| Dec 31, 2025 | 1,386.26% |
| Sep 30, 2025 | -1,153.62% |
| Jun 30, 2025 | -433.55% |
| Mar 31, 2025 | -1,216.52% |
| Dec 31, 2024 | -13.36% |
| Sep 30, 2024 | -315.70% |
| Jun 30, 2024 | -302.37% |
| Mar 31, 2024 | -275.01% |
| Dec 31, 2023 | 514.15% |
| Sep 30, 2023 | -555.31% |
| Jun 30, 2023 | -6.38% |
| Mar 31, 2023 | -302.83% |
| Dec 31, 2022 | -383.92% |
| Sep 30, 2022 | -321.49% |
| Jun 30, 2022 | 11.87% |
| Mar 31, 2022 | -180.29% |
| Dec 31, 2021 | -185.77% |
| Sep 30, 2021 | 69.25% |
| Jun 30, 2021 | -842.34% |