Q32 Bio QTTB Institutional Ownership

NASDAQ QTTB

$8.80 +0.13 (+1.50%)

At close: Oct 22, 2026 · 4:00 PM EDT

Institutions by Trading Activity

72 Institutions

Increased 45 62.5%

Unchanged 13 18.1%

Reduced 14 19.4%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

93.44%

▲+29.01 pp QoQ

Shares Held by Institutions

22.18Mn

of 23.74Mn outstanding

▲+135.31% QoQ

Shares Outstanding

23.74Mn

1.56Mn held outside 13F filers

Institutional Investors

filed 13F for Jun 2026

▲+19 vs prior quarter

Net Shares Added (QoQ)

+12.75Mn

accumulated since last quarter

Value of Holdings

$192.29Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Q32 Bio Inc. (NASDAQ:QTTB) counted 72 institutional investors among its 13F-reported shareholders for the quarter ended June 30, 2026.

These investors held 93.44% of outstanding shares in Q2 2026, up from 64.43% the quarter before.
Total shares held in QTTB rose 135.31% from Q1 2026; the number of holders rose 22.03% from Q2 2025.
Looking at the 72 holders of QTTB individually, 45 added to their positions, 14 reduced their stakes and 13 left their positions unchanged.
Combined, institutional investors held 22.18Mn shares of QTTB as of Q2 2026, up 12.75Mn from the prior quarter and up 13.22Mn from a year earlier.
As of June 30, 2026, OrbiMed Advisors LLC held the largest stake in Q32 Bio with 4.13Mn shares, or 17.39% of shares outstanding.
The biggest increases in QTTB positions during Q2 2026 came from OrbiMed Advisors LLC (+1.88Mn shares), Atlas Venture Life Science Advisors, LLC (+625K shares), American Century Companies Inc (+253.98K shares), Vanguard Capital Management LLC (+212.4K shares) and Citadel Advisors LLC (+105.18K shares).
Among holders that kept a stake in Q32 Bio, the biggest sellers in Q2 2026 were Carlyle Group Inc. (-1.04Mn shares), Opaleye Management Inc. (-325.23K shares), Acorn Capital Advisors, LLC (-98.88K shares), Renaissance Technologies LLC (-27.32K shares) and Cambridge Investment Research Advisors, Inc. (-16.94K shares).
According to Business Quant data, the leading holders of QTTB for Q2 2026 were OrbiMed Advisors LLC (4.13Mn shares), Boxer Capital Management, LLC (3.15Mn shares), Atlas Venture Life Science Advisors, LLC (2.72Mn shares), BVF Inc (2.35Mn shares), Ra Capital Management, L.P. (2.33Mn shares), Point72 Asset Management, L.P. (1.17Mn shares), Opaleye Management Inc. (931K shares), Logos Global Management LP (800K shares), SummitTX Capital, L.P. (733.77K shares) and Vanguard Capital Management LLC (518.8K shares).

Form 13F Holdings

72 Institutional Holders

Report period 30 Jun, 2026

Total shares held 22.18Mn

Of outstanding 93.44%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	ORBIMED ADVISORS LLC	0001055951	4,127,987	17.39%	▲1,875,000	+83.22%	$52.59Mn
2	Boxer Capital Management, LLC	0002018299	3,149,310	13.27%	▲3,149,310	0.00%	$40.12Mn
3	Atlas Venture Life Science Advisors, LLC	0001917529	2,717,106	11.45%	▲625,000	+29.87%	$34.62Mn
4	BVF INC/IL	0001056807	2,350,000	9.90%	▲2,350,000	0.00%	$29.94Mn
5	RA CAPITAL MANAGEMENT, L.P.	0001346824	2,332,457	9.83%	▲2,332,457	0.00%	$29.72Mn
6	Point72 Asset Management, L.P.	0001603466	1,173,396	4.94%	▲1,173,396	0.00%	$14.95Mn
7	Opaleye Management Inc.	0001595855	931,000	3.92%	▼325,228	-25.89%	$11.86Mn
8	Logos Global Management LP	0001792126	800,000	3.37%	▲800,000	0.00%	$10.19Mn
9	SummitTX Capital, L.P.	0002052310	733,774	3.09%	▲733,774	0.00%	$9.35Mn
10	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	518,803	2.19%	▲212,402	+69.32%	$6.61Mn
11	Ikarian Capital, LLC	0001778253	430,000	1.81%	▲430,000	0.00%	$5.48Mn
12	Woodline Partners LP	0001784547	286,212	1.21%	▲286,212	0.00%	$3.65Mn
13	AMERICAN CENTURY COMPANIES INC	0000748054	272,752	1.15%	▲253,982	+1,353.13%	$3.47Mn
14	Sanofi	0001121404	244,083	1.03%	0	0.00%	$3.11Mn
15	ACADIAN ASSET MANAGEMENT LLC	0000916542	218,234	0.92%	▲45,648	+26.45%	$2.78K
16	ACORN CAPITAL ADVISORS, LLC	0002054410	216,171	0.91%	▼98,881	-31.39%	$2.75Mn
17	RENAISSANCE TECHNOLOGIES LLC	0001037389	179,600	0.76%	▼27,315	-13.20%	$2.29Mn
18	JANE STREET GROUP, LLC	0001595888	162,747	0.69%	▲97,148	+148.09%	$2.07Mn
19	MONIMUS CAPITAL MANAGEMENT, LP	0001848831	132,036	0.56%	▼2,274	-1.69%	$1.68Mn
20	BOOTHBAY FUND MANAGEMENT, LLC	0001549230	130,427	0.55%	▲130,427	0.00%	$1.66Mn

Showing 1 to 20 of 72 holders