Milestone Pharmaceuticals MIST Institutional Ownership

NASDAQ MIST

$0.70 -0.02 (-3.23%)

At close: Oct 21, 2026 · 4:00 PM EDT

As of the 13F quarter ended Jun 30, 2026, 79 institutions held 35.73% of Milestone Pharmaceuticals (MIST) shares outstanding. Versus the prior quarter, institutional ownership was up 5.91 percentage points, the holder count fell by 6 and shares held were up 27.55%. The largest holder is Pavaki Capital Management LLC with 9.07Mn shares (6.54% of outstanding).

Updated Oct 5, 2026 Milestone Pharmaceuticals (MIST) stock price and overview

Institutions by Trading Activity

79 Institutions

Increased 31 39.2%

Unchanged 25 31.6%

Reduced 23 29.1%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

35.73%

▲+5.91 pp QoQ

Shares Held by Institutions

49.55Mn

of 138.69Mn outstanding

▲+27.55% QoQ

Shares Outstanding

138.69Mn

89.14Mn held outside 13F filers

Institutional Investors

filed 13F for Jun 2026

▼-6 vs prior quarter

Net Shares Added (QoQ)

+10.70Mn

accumulated since last quarter

Value of Holdings

$35.68Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 5, 2026

Milestone Pharmaceuticals Inc. (NASDAQ:MIST) appeared in the 13F filings of 79 institutional investors for the quarter ended June 30, 2026.

These investors held 35.73% of outstanding shares in Q2 2026, up from 29.82% the quarter before.
Total holdings of MIST shares rose 27.55% from Q1 2026, and the holder count rose 92.68% from Q2 2025.
Among the 79 holders of Milestone Pharmaceuticals, 31 added to their positions, 23 reduced their stakes and 25 left their positions unchanged.
Institutional investors held 49.55Mn shares of Milestone Pharmaceuticals in total at the end of Q2 2026, up 10.7Mn from the prior quarter and up 38.57Mn from a year earlier.
As of June 30, 2026, Pavaki Capital Management LLC held the largest stake in Milestone Pharmaceuticals with 9.07Mn shares, or 6.54% of shares outstanding.
Among existing holders, the largest additions to Milestone Pharmaceuticals in Q2 2026 came from Point72 Asset Management, L.P. (+4.33Mn shares), Propel Bio Management, LLC (+3.31Mn shares), Simplify Asset Management Inc. (+1.84Mn shares), Millennium Management LLC (+1.6Mn shares) and RTW Investments, LP (+1.5Mn shares).
Holders that trimmed the most shares of Milestone Pharmaceuticals in Q2 2026 while keeping a position were Balyasny Asset Management L.P. (-630.83K shares), Two Sigma Investments, LP (-277.16K shares), Citadel Advisors LLC (-163.81K shares), Susquehanna International Group, LLP (-159.15K shares) and Marshall Wace, LLP (-146.84K shares).
According to Business Quant data, the leading holders of MIST for Q2 2026 were Pavaki Capital Management LLC (9.07Mn shares), RTW Investments, LP (7.83Mn shares), Propel Bio Management, LLC (7.43Mn shares), Point72 Asset Management, L.P. (5.41Mn shares), Simplify Asset Management Inc. (3.35Mn shares), Millennium Management LLC (3.14Mn shares), Two Sigma Investments, LP (2.04Mn shares), Marshall Wace, LLP (1.8Mn shares), Kalehua Capital Management LLC (1.27Mn shares) and Lion Point Capital, LP (820K shares).

Form 13F Holdings

79 Institutional Holders

Report period 30 Jun, 2026

Total shares held 49.55Mn

Of outstanding 35.73%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Pavaki Capital Management LLC	0002143027	9,067,848	6.54%	▲5,000	+0.06%	$12.15Mn
2	RTW INVESTMENTS, LP	0001493215	7,833,336	5.65%	▲1,502,335	+23.73%	$10.50Mn
3	Propel Bio Management, LLC	0001969764	7,429,590	5.36%	▲3,311,269	+80.40%	$9.96Mn
4	Point72 Asset Management, L.P.	0001603466	5,411,138	3.90%	▲4,325,455	+398.41%	$7.25Mn
5	Simplify Asset Management Inc.	0001846368	3,349,379	2.41%	▲1,842,974	+122.34%	$4.49Mn
6	MILLENNIUM MANAGEMENT LLC	0001273087	3,142,219	2.27%	▲1,597,894	+103.47%	$4.21Mn
7	TWO SIGMA INVESTMENTS, LP	0001179392	2,040,015	1.47%	▼277,161	-11.96%	$2.73Mn
8	MARSHALL WACE, LLP	0001318757	1,797,695	1.30%	▼146,835	-7.55%	$2.41Mn
9	Kalehua Capital Management LLC	0002106181	1,269,237	0.92%	▲1,269,237	0.00%	$1.70Mn
10	Lion Point Capital, LP	0001643354	820,000	0.59%	0	0.00%	$1.10Mn
11	Toronto Dominion Bank	0000947263	750,000	0.54%	0	0.00%	$1.01Mn
12	Ameriprise Financial Inc	0000820027	666,666	0.48%	▲666,666	0.00%	$893.33K
12	Boxer Capital Management, LLC	0002018299	666,666	0.48%	0	0.00%	$893.33K
13	Morgan Stanley	0000895421	635,211	0.46%	▼88,930	-12.28%	$851.18K
14	UBS Group AG	0001610520	465,403	0.34%	▼29,505	-5.96%	$623.64K
15	BOOTHBAY FUND MANAGEMENT, LLC	0001549230	462,669	0.33%	▲293,994	+174.30%	$619.98K
16	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0001446194	359,895	0.26%	▼159,151	-30.66%	$482.26K
17	GUARDIAN WEALTH ADVISORS, LLC / NC	0001901403	339,450	0.24%	▲59,200	+21.12%	$454.86K
17	Aptus Capital Advisors, LLC	0001664193	339,450	0.24%	▲59,200	+21.12%	$454.86K
18	Seven Fleet Capital Management LP	0002092021	270,233	0.19%	▼63,100	-18.93%	$362.11K

Showing 1 to 20 of 79 holders