As of the 13F quarter ended Jun 30, 2026, 192 institutions held 30.98% of Structure Therapeutics (GPCR) shares outstanding. Versus the prior quarter, institutional ownership was up 0.29 percentage points, the holder count fell by 2 and shares held were up 1.25%. The largest holder is FMR LLC with 7.81Mn shares (3.58% of outstanding).
Structure Therapeutics Inc. (NASDAQ:GPCR) was held by 192 institutional investors that filed 13F reports for the quarter ended June 30, 2026.
| # | Institution | CIK | Shares Held | % of Outstanding | Change (QoQ) | Change (%) | Value (USD) |
|---|---|---|---|---|---|---|---|
| 1 | FMR LLC | 0000315066 | 7,810,306 | 3.58% | ▼593,143 | -7.06% | $419.18Mn |
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 0000902219 | 7,379,433 | 3.39% | ▲119,146 | +1.64% | $396.05Mn |
| 3 | Avoro Capital Advisors LLC | 0001633313 | 6,555,555 | 3.01% | 0 | 0.00% | $351.84Mn |
| 4 | Jupiter Topco LLC | 0002146052 | 5,204,212 | 2.39% | ▲5,204,212 | 0.00% | $279.34Mn |
| 5 | Deep Track Capital, LP | 0001856083 | 4,740,072 | 2.17% | ▲460,224 | +10.75% | $254.40Mn |
| 6 | BVF INC/IL | 0001056807 | 3,366,823 | 1.54% | ▼92,535 | -2.67% | $180.70Mn |
| 7 | Morgan Stanley | 0000895421 | 2,806,640 | 1.29% | ▲501,183 | +21.74% | $150.63Mn |
| 8 | ORBIMED ADVISORS LLC | 0001055951 | 2,209,400 | 1.01% | ▲733,997 | +49.75% | $118.58Mn |
| 9 | Principal Financial Group Inc | 0001126328 | 1,752,753 | 0.80% | ▼1,011 | -0.06% | $94.07Mn |
| 10 | AMERICAN CENTURY COMPANIES INC | 0000748054 | 1,682,179 | 0.77% | ▲244,148 | +16.98% | $90.28Mn |
| 11 | RTW INVESTMENTS, LP | 0001493215 | 1,607,507 | 0.74% | ▲1,607,507 | 0.00% | $86.27Mn |
| 12 | DRIEHAUS CAPITAL MANAGEMENT LLC | 0000938206 | 1,553,219 | 0.71% | ▼24,137 | -1.53% | $83.36Mn |
| 13 | BAKER BROS. ADVISORS LP | 0001263508 | 1,432,529 | 0.66% | 0 | 0.00% | $76.88Mn |
| 14 | Casdin Capital, LLC | 0001534261 | 1,175,000 | 0.54% | 0 | 0.00% | $63.06Mn |
| 15 | DEERFIELD MANAGEMENT COMPANY, L.P. | 0001009258 | 1,086,000 | 0.50% | ▲318,007 | +41.41% | $58.29Mn |
| 16 | CAPITOLIS LIQUID GLOBAL MARKETS LLC | 0002094379 | 1,041,100 | 0.48% | ▼110,200 | -9.57% | $55.88Mn |
| 17 | Siren, L.L.C. | 0002005245 | 872,967 | 0.40% | ▼455,731 | -34.30% | $46.85Mn |
| 18 | PRICE T ROWE ASSOCIATES INC /MD/ | 0000080255 | 845,532 | 0.39% | ▼1,155,164 | -57.74% | $45.38K |
| 19 | PACIFIC HEIGHTS ASSET MANAGEMENT LLC | 0001323414 | 800,000 | 0.37% | ▲50,000 | +6.67% | $42.94Mn |
| 20 | Rock Springs Capital Management LP | 0001595725 | 640,317 | 0.29% | ▲100 | +0.02% | $34.37Mn |