Zevra Therapeutics (ZVRA) Operating Margin (2019 - 2026)
Zevra Therapeutics' Operating Margin was 42.26% in Q2 2026, up 316.54 percentage points from -274.28% a year earlier but down 101.71 percentage points from the prior quarter.
Zevra Therapeutics (ZVRA) Operating Margin (2019 - 2026) Analysis & Trends
On a trailing twelve-month basis, Zevra Therapeutics' Operating Margin was 60.50% through Jun 30, 2026, up 252.59 percentage points year-over-year; for FY2025, it was -59.10%, up 309.37 percentage points from FY2024.
- Operating Margin shows a five-year change of -16.89 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was -368.47% in FY2024 (-187.84 pp), -180.63% in FY2023 (+238.27 pp), -418.91% in FY2022 (-445.88 pp) and 26.98% in FY2021 (+69.19 pp).
- Quarterly Operating Margin has moved between -1905.15% (Q2 2022) and 143.97% (Q1 2026) over five years.
- Compared with a year earlier, Operating Margin has increased for six straight quarters, with an average year-over-year change of +251.30 percentage points over the last eight quarters.
- The best year-over-year quarter for Operating Margin over five years was Q2 2023 (a gain of 1831.34 percentage points); the worst was Q2 2022 (a drop of 1953.82 percentage points).
- Per Business Quant data, ZVRA's Operating Margin in the three quarters before Q2 2026 was 143.97% (Q1 2026), 27.27% (Q4 2025) and 15.87% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Zevra Therapeutics | 672.94 Mn | -139.77 Mn | 38.18 Mn | 42.26% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 42.26% |
| Mar 31, 2026 | 143.97% |
| Dec 31, 2025 | 27.27% |
| Sep 30, 2025 | 15.87% |
| Jun 30, 2025 | -274.28% |
| Mar 31, 2025 | -26.28% |
| Dec 31, 2024 | -128.34% |
| Sep 30, 2024 | -738.00% |
| Jun 30, 2024 | -534.84% |
| Mar 31, 2024 | -598.13% |
| Dec 31, 2023 | -117.31% |
| Sep 30, 2023 | -530.71% |
| Jun 30, 2023 | -73.81% |
| Mar 31, 2023 | -404.00% |
| Dec 31, 2022 | -460.58% |
| Sep 30, 2022 | -230.55% |
| Jun 30, 2022 | -1,905.15% |
| Mar 31, 2022 | -46.89% |
| Dec 31, 2021 | -110.07% |
| Sep 30, 2021 | -113.08% |
Zevra Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ZVRA&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ZVRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ZVRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();