Zevra Therapeutics (ZVRA) Operating Margin (2019 - 2026)
Zevra Therapeutics' (ZVRA) quarterly Operating Margin came in at 143.97% in Q1 2026, up 17025.0% YoY from N/an in Q1 2025, and up 428.12% on a QoQ basis from 27.26% in Q4 2025.
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Zevra Therapeutics (ZVRA) Operating Margin (2019 - 2026) Analysis & Trends
Zevra Therapeutics (ZVRA) has 8 years of Operating Margin data on file, last reported at 143.97% in Q1 2026.
- Quarterly Operating Margin rose 17025.0% year-over-year to 143.97% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 4.44% (up 17301.0% YoY) and the FY2025 annual result came in at 59.12%, up 30935.0% from the prior year.
- Operating Margin advanced to 143.97% in Q1 2026, from 27.26% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 143.97% in Q1 2026 to a low of 1978.19% in Q2 2022.
- A 5-year average of 370.34% and a median of 257.67% in 2022 frame the typical range for Operating Margin.
- Annual changes were most pronounced in 2022 — Operating Margin slumped 202686 bps — and 2023, when it surged 190438 bps.
- Tracing ZVRA's Operating Margin over 5 years: stood at 460.58% in 2022, then soared by 75 bps to 117.31% in 2023, then declined by 9 bps to 128.34% in 2024, then soared by 121 bps to 27.26% in 2025, then soared by 428 bps to 143.97% in 2026.
- The last three Operating Margin figures came in at 143.97% (Q1 2026), 27.26% (Q4 2025), and 15.9% (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -562.07% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 19.06% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 17.93% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 19.75% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -0.36% |
| 10 | Zevra Therapeutics | 734.60 Mn | 513.03 Mn | 38.18 Mn | 42.26% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 42.26% |
| Mar 31, 2026 | 143.97% |
| Dec 31, 2025 | 27.27% |
| Sep 30, 2025 | 15.87% |
| Jun 30, 2025 | -274.28% |
| Mar 31, 2025 | -26.28% |
| Dec 31, 2024 | -128.34% |
| Sep 30, 2024 | -738.00% |
| Jun 30, 2024 | -534.84% |
| Mar 31, 2024 | -598.13% |
| Dec 31, 2023 | -117.31% |
| Sep 30, 2023 | -530.71% |
| Jun 30, 2023 | -73.81% |
| Mar 31, 2023 | -404.00% |
| Dec 31, 2022 | -460.58% |
| Sep 30, 2022 | -230.55% |
| Jun 30, 2022 | -1,905.15% |
| Mar 31, 2022 | -46.89% |
| Dec 31, 2021 | -110.07% |
| Sep 30, 2021 | -113.08% |