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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInterest Coverage RatioInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Xencor (XNCR) Operating Margin (2016 - 2025)

Xencor (XNCR) has disclosed Operating Margin for 5 consecutive years, with 189.92% as the latest value for Q4 2025.

  • On a quarterly basis, Operating Margin fell 16496.0% to 189.92% in Q4 2025 year-over-year; TTM through Dec 2025 was 141.35%, a 2012.0% increase, with the full-year FY2025 number at 141.35%, up 2012.0% from a year prior.
  • Operating Margin was 189.92% for Q4 2025 at Xencor, up from 226.29% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 24.96% in Q4 2024 to a low of 341.71% in Q1 2024.
  • A 3-year average of 166.17% and a median of 160.93% in 2025 define the central range for Operating Margin.
  • Peak YoY movement for Operating Margin: plummeted -27930bps in 2024, then skyrocketed 20978bps in 2025.
  • Xencor's Operating Margin stood at 53.72% in 2023, then skyrocketed by 54bps to 24.96% in 2024, then plummeted by -661bps to 189.92% in 2025.
  • Per Business Quant, the three most recent readings for XNCR's Operating Margin are 189.92% (Q4 2025), 226.29% (Q3 2025), and 76.07% (Q2 2025).