Xencor (XNCR) Operating Margin (2013 - 2026)
Xencor (XNCR) reported Operating Margin of -72.37% for Q2 2026, up 3.70 percentage points from -76.07% a year earlier and up 1651.77 percentage points from the prior quarter.
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Analysis
Xencor (XNCR) Operating Margin (2013 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Xencor's Operating Margin came in at -205.84%, down 107.34 percentage points year-over-year; for FY2025, it came in at -141.35%, up 20.12 percentage points from FY2024.
- Operating Margin has a five-year change of -78.76 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at -161.47% in FY2024 (-85.66 pp), -75.80% in FY2023 (-25.70 pp), -50.11% in FY2022 (-66.01 pp) and 15.91% in FY2021 (+78.50 pp).
- The Q2 2026 figure ranks as the highest quarterly Operating Margin since Q4 2024.
- Year over year, Operating Margin gained in five of the last eight quarters, with an average year-over-year change of -194.36 percentage points.
- The high point for year-over-year Operating Margin in five years was Q1 2025 (a gain of 209.78 percentage points); the low point was Q1 2026 (a drop of 1592.21 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -1724.14% (Q1 2026), -189.92% (Q4 2025) and -226.29% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Xencor | 1.86 Bn | 274.02 Mn | - | -72.37% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -72.37% |
| Mar 31, 2026 | -1,724.14% |
| Dec 31, 2025 | -189.92% |
| Sep 30, 2025 | -226.29% |
| Jun 30, 2025 | -76.07% |
| Mar 31, 2025 | -131.93% |
| Dec 31, 2024 | -24.96% |
| Sep 30, 2024 | -310.17% |
| Jun 30, 2024 | -231.61% |
| Mar 31, 2024 | -341.71% |
| Dec 31, 2023 | -53.67% |
| Sep 30, 2023 | -30.86% |
| Jun 30, 2023 | -57.11% |
| Mar 31, 2023 | -319.71% |
| Dec 31, 2022 | -197.19% |
| Sep 30, 2022 | -140.47% |
| Jun 30, 2022 | -92.72% |
| Mar 31, 2022 | 30.95% |
| Dec 31, 2021 | 59.51% |
| Sep 30, 2021 | -209.64% |
API Access
Xencor Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=XNCR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "XNCR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=XNCR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();