Vanda Pharmaceuticals (VNDA) Operating Margin (2010 - 2026)
Vanda Pharmaceuticals (VNDA) reported Operating Margin of -126.28% for Q2 2026, down 53.07 percentage points from -73.21% a year earlier and down 29.17 percentage points from the prior quarter.
Vanda Pharmaceuticals (VNDA) Operating Margin (2010 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Vanda Pharmaceuticals' Operating Margin came in at -86.07%, down 36.52 percentage points year-over-year; for FY2025, it came in at -69.95%, down 49.50 percentage points from FY2024.
- Operating Margin has declined for four consecutive years, with a five-year change of -80.93 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at -20.46% in FY2024 (-13.21 pp), -7.24% in FY2023 (-9.73 pp), 2.49% in FY2022 (-13.21 pp) and 15.69% in FY2021 (+4.72 pp).
- The Q2 2026 figure ranks as the lowest quarterly Operating Margin since Q2 2014.
- Year over year, Operating Margin has now declined in each of the last 13 quarters, with an average year-over-year change of -34.86 percentage points over the last eight quarters.
- The high point for year-over-year Operating Margin in five years was Q1 2023 (a gain of 15.95 percentage points); the low point was Q1 2025 (a drop of 62.53 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -97.11% (Q1 2026), -70.53% (Q4 2025) and -55.61% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Vanda Pharmaceuticals | 304.09 Mn | -625.85 Mn | 46.97 Mn | -126.28% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -126.28% |
| Mar 31, 2026 | -97.11% |
| Dec 31, 2025 | -70.53% |
| Sep 30, 2025 | -55.61% |
| Jun 30, 2025 | -73.21% |
| Mar 31, 2025 | -81.99% |
| Dec 31, 2024 | -19.33% |
| Sep 30, 2024 | -23.08% |
| Jun 30, 2024 | -20.10% |
| Mar 31, 2024 | -19.46% |
| Dec 31, 2023 | -15.67% |
| Sep 30, 2023 | -15.45% |
| Jun 30, 2023 | -6.23% |
| Mar 31, 2023 | 3.21% |
| Dec 31, 2022 | 10.28% |
| Sep 30, 2022 | 5.98% |
| Jun 30, 2022 | 5.38% |
| Mar 31, 2022 | -12.74% |
| Dec 31, 2021 | 12.70% |
| Sep 30, 2021 | 15.43% |
Vanda Pharmaceuticals Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=VNDA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "VNDA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=VNDA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();