Growth Metrics

Vanda Pharmaceuticals (VNDA) Operating Margin (2016 - 2025)

Vanda Pharmaceuticals' Operating Margin history spans 16 years, with the latest figure at 70.53% for Q4 2025.

  • On a quarterly basis, Operating Margin fell 5120.0% to 70.53% in Q4 2025 year-over-year; TTM through Dec 2025 was 69.95%, a 4950.0% decrease, with the full-year FY2025 number at 69.95%, down 4950.0% from a year prior.
  • Operating Margin hit 70.53% in Q4 2025 for Vanda Pharmaceuticals, down from 55.61% in the prior quarter.
  • Over the last five years, Operating Margin for VNDA hit a ceiling of 18.22% in Q2 2021 and a floor of 81.99% in Q1 2025.
  • Historically, Operating Margin has averaged 16.28% across 5 years, with a median of 14.09% in 2023.
  • Biggest five-year swings in Operating Margin: skyrocketed 1672bps in 2021 and later tumbled -6253bps in 2025.
  • Tracing VNDA's Operating Margin over 5 years: stood at 12.7% in 2021, then decreased by -19bps to 10.28% in 2022, then plummeted by -252bps to 15.67% in 2023, then fell by -23bps to 19.33% in 2024, then tumbled by -265bps to 70.53% in 2025.
  • Business Quant data shows Operating Margin for VNDA at 70.53% in Q4 2025, 55.61% in Q3 2025, and 73.21% in Q2 2025.