Entrada Therapeutics (TRDA) Operating Margin (2023 - 2026)
Entrada Therapeutics (TRDA) recorded quarterly Operating Margin of 4834.63% in Q1 2026, down 48.79% quarter-over-quarter from 3249.27% in Q4 2025, and down 472864.0% on a YoY basis from N/an in Q1 2025.
Entrada Therapeutics (TRDA) Operating Margin (2023 - 2026) Analysis & Trends
Entrada Therapeutics' Operating Margin history runs 4 years deep, the most recent figure standing at 4834.63% for Q1 2026.
- In Q1 2026, Operating Margin fell 472864.0% year-over-year to 4834.63%; the TTM figure through Mar 2026 stood at 3109.29% (down 311167.0% YoY), while the FY2025 annual figure was 621.13%, down 64344.0% from the prior year.
- Operating Margin was 4834.63% for Q1 2026 at Entrada Therapeutics, down from 3249.27% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 56.42% in Q2 2024 to a low of 4834.63% in Q1 2026.
- Historically, Operating Margin has averaged 1046.97% across 4 years, with a median of 89.7% in 2023.
- The sharpest annual moves came in 2024 and 2026: Operating Margin jumped 14612 bps in 2024, then plunged 472864 bps in 2026.
- A 4-year view of Operating Margin shows it stood at 11.72% in 2023, then tumbled by 234 bps to 15.69% in 2024, then tumbled by 20612 bps to 3249.27% in 2025, then slumped by 49 bps to 4834.63% in 2026.
- The last three Operating Margin figures came in at 4834.63% (Q1 2026), 3249.27% (Q4 2025), and 2915.18% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Entrada Therapeutics | 295.36 Mn | 295.36 Mn | - | -4,834.63% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -4,834.63% |
| Dec 31, 2025 | -3,249.27% |
| Sep 30, 2025 | -2,915.18% |
| Jun 30, 2025 | -2,402.51% |
| Mar 31, 2025 | -105.99% |
| Dec 31, 2024 | -15.69% |
| Sep 30, 2024 | -110.67% |
| Jun 30, 2024 | 56.42% |
| Mar 31, 2024 | 35.71% |
| Dec 31, 2023 | 11.72% |
| Sep 30, 2023 | 32.04% |
| Jun 30, 2023 | -89.70% |
| Mar 31, 2023 | -22.88% |