Spyre Therapeutics SYRE Insider Ownership

NASDAQ SYRE
$92.95 +1.55 (+1.70%)
At close: Oct 21, 2026 · 4:00 PM EDT

Insider Holdings by Owner

1.54Mn Shares

Insider Ownership Statistics

as of 30 Sep, 2026
Insider Ownership
1.80%
▼-0.093% pp QoQ
Shares Held by Insiders
1.53Mn
filed for Sep 2026
▼-4.89% QoQ
Shares Outstanding
84.73Mn
84,729,435 shares
Direct Holdings
703.75K
Indirect: 821.44K
Net Shares Traded (QoQ)
-78.39K
net selling in Sep 2026
Insiders Holding Shares
10
with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding
Latest —
Average ownership —
Peak ownership —

Shares Purchased/Sold by Insiders

Bought Sold
Latest quarter —
Net over range —
Buying quarters —

Insider Ownership Summary

Over the past year, SYRE insiders sold $442.98 million of stock (5.29Mn shares) on the open market and bought none.

Form 4 Holdings

Insiders Holding SYRE

Insiders 10
Shares held 1.54Mn
Of outstanding 1.82%
# Insider Position Direct Indirect Total Share of Insiders Last Filed
1 Funds Management Llc Fairmount Director, TenPercentOwner 0 812,076 812,076 52.6% 29 Dec, 2023
2 Cameron Turtle Chief Executive Officer 537,540 0 537,540 34.8% 02 Oct, 2026
3 Scott L Burrows Chief Financial Officer 79,762 0 79,762 5.2% 02 Oct, 2026
4 Michael Thomas Henderson Director 68,606 0 68,606 4.4% 23 Jun, 2026
5 Anthony G. Quinn President Ceo 22,022 0 22,022 1.4% 18 Mar, 2022
6 Jeffrey W. Albers Director 0 9,360 9,360 0.6% 10 Aug, 2026
7 Jonathan Alspaugh Chief Financial Officer 6,615 0 6,615 0.4% 15 Mar, 2022
8 Marcio Souza Director 3,600 0 3,600 0.2% 25 Aug, 2022
9 Heidy King-Jones Officer 2,845 0 2,845 0.2% 02 Oct, 2026
10 Jr. Michael Conick Hanley Chief Commercial Officer 1,448 0 1,448 0.1% 10 Jun, 2022

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

407 Insider Transactions

Source SEC Form 4
Latest quarter Sep 2026
Download Data
Date Insider Position Transaction Shares Price Value Shares Held After Ownership
01 Oct, 2026 Cameron Turtle Chief Executive Officer Disposed S 600 $89.14 $53.48K 551,940 Direct
30 Sep, 2026 Scott L Burrows Chief Financial Officer Acquired M 17,500 $14.50 $253.75K 97,262 Direct
01 Oct, 2026 Heidy King-Jones Officer Acquired M 28,933 $14.50 $419.53K 31,778 Direct
30 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed S 17,500 $89.89 $1.57Mn 79,762 Direct
01 Oct, 2026 Heidy King-Jones Officer Disposed S 400 $89.24 $35.70K 31,378 Direct
01 Oct, 2026 Cameron Turtle Chief Executive Officer Disposed S 2,683 $90.10 $241.74K 549,257 Direct
01 Oct, 2026 Cameron Turtle Chief Executive Officer Disposed S 2,638 $91.49 $241.35K 546,619 Direct
01 Oct, 2026 Heidy King-Jones Officer Disposed S 16,605 $90.35 $1.50Mn 14,773 Direct
01 Oct, 2026 Scott L Burrows Chief Financial Officer Acquired M 7,500 $14.50 $108.75K 87,262 Direct
01 Oct, 2026 Cameron Turtle Chief Executive Officer Disposed S 3,989 $92.31 $368.22K 542,630 Direct
01 Oct, 2026 Heidy King-Jones Officer Disposed S 7,228 $91.35 $660.28K 7,545 Direct
01 Oct, 2026 Scott L Burrows Chief Financial Officer Disposed S 600 $89.07 $53.44K 86,662 Direct
01 Oct, 2026 Cameron Turtle Chief Executive Officer Disposed S 4,990 $93.37 $465.92K 537,640 Direct
01 Oct, 2026 Scott L Burrows Chief Financial Officer Disposed S 1,500 $90.27 $135.41K 85,162 Direct
01 Oct, 2026 Heidy King-Jones Officer Disposed S 2,100 $92.70 $194.67K 5,445 Direct
01 Oct, 2026 Scott L Burrows Chief Financial Officer Disposed S 2,100 $91.92 $193.03K 83,062 Direct
01 Oct, 2026 Cameron Turtle Chief Executive Officer Disposed S 100 $93.91 $9.39K 537,540 Direct
01 Oct, 2026 Heidy King-Jones Officer Disposed S 2,600 $93.46 $243.00K 2,845 Direct
01 Oct, 2026 Scott L Burrows Chief Financial Officer Disposed S 3,071 $92.95 $285.45K 79,991 Direct
01 Oct, 2026 Heidy King-Jones Officer Disposed M 28,933 $0.00 $0 482,478 Direct