Sarepta Therapeutics (SRPT) Operating Margin (2010 - 2026)
Sarepta Therapeutics' Operating Margin was 3.31% in Q2 2026, down 15.60 percentage points from 18.91% a year earlier and down 45.73 percentage points from the prior quarter.
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Analysis
Sarepta Therapeutics (SRPT) Operating Margin (2010 - 2026) Analysis & Trends
On a trailing twelve-month basis, Sarepta Therapeutics' Operating Margin was -7.26% through Jun 30, 2026, down 7.22 percentage points year-over-year; for FY2025, it was -31.83%, down 43.30 percentage points from FY2024.
- Operating Margin shows a five-year change of +72.62 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was 11.47% in FY2024 (+33.01 pp), -21.54% in FY2023 (+35.93 pp), -57.47% in FY2022 (+8.03 pp) and -65.50% in FY2021 (+38.96 pp).
- Quarterly Operating Margin has moved between -92.92% (Q4 2025) and 49.05% (Q1 2026) over five years.
- Compared with a year earlier, Operating Margin was higher in four of the last eight quarters, with an average year-over-year change of -9.33 percentage points.
- The best year-over-year quarter for Operating Margin over five years was Q1 2026 (a gain of 89.37 percentage points); the worst was Q4 2025 (a drop of 117.48 percentage points).
- Per Business Quant data, SRPT's Operating Margin in the three quarters before Q2 2026 was 49.05% (Q1 2026), -92.92% (Q4 2025) and -25.89% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Sarepta Therapeutics | 1.97 Bn | -1.26 Bn | 251.87 Mn | 3.31% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 3.31% |
| Mar 31, 2026 | 49.05% |
| Dec 31, 2025 | -92.92% |
| Sep 30, 2025 | -25.89% |
| Jun 30, 2025 | 18.91% |
| Mar 31, 2025 | -40.33% |
| Dec 31, 2024 | 24.56% |
| Sep 30, 2024 | 4.75% |
| Jun 30, 2024 | -0.19% |
| Mar 31, 2024 | 8.44% |
| Dec 31, 2023 | 6.21% |
| Sep 30, 2023 | -6.28% |
| Jun 30, 2023 | -51.11% |
| Mar 31, 2023 | -54.47% |
| Dec 31, 2022 | -41.34% |
| Sep 30, 2022 | -57.04% |
| Jun 30, 2022 | -90.43% |
| Mar 31, 2022 | -41.21% |
| Dec 31, 2021 | -52.52% |
| Sep 30, 2021 | -18.19% |
API Access
Sarepta Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=SRPT&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "SRPT", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=SRPT&period=max&api_key=YOUR_API_KEY");
const data = await res.json();