Sangamo Therapeutics (SGMOQ) Operating Margin (2010 - 2025)
Sangamo Therapeutics' Operating Margin came in at -268.51% for Q4 2025, up 75.69 percentage points from -344.19% a year earlier and up 5850.77 percentage points from the prior quarter.
Sangamo Therapeutics (SGMOQ) Operating Margin (2010 - 2025) Analysis & Trends
For FY2025, Sangamo Therapeutics' Operating Margin was -306.53%, down 126.65 percentage points from FY2024.
- Operating Margin carries a five-year change of -196.92 percentage points (FY2020 to FY2025).
- Going back by year, Operating Margin was -179.88% in FY2024 (-24.40 pp), -155.48% in FY2023 (+25.37 pp), -180.85% in FY2022 (-15.23 pp) and -165.61% in FY2021 (-56.00 pp).
- The five-year range for quarterly Operating Margin is -10712.27% (Q1 2024) to 21.52% (Q3 2024).
- Year-over-year, Operating Margin increased in five of the last eight quarters, with an average year-over-year change of -122.21 percentage points.
- The fastest year-over-year change in Operating Margin over five years came in Q2 2025 (a gain of 10319.32 percentage points), and the weakest in Q1 2024 (a drop of 10723.68 percentage points).
- Business Quant data shows SGMOQ's Operating Margin at -6119.28% (Q3 2025), -97.54% (Q2 2025) and -460.28% (Q1 2025) in the three quarters before Q4 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Sangamo Therapeutics | 39.23 Mn | -74.88 Mn | - | -268.51% |
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -268.51% |
| Sep 30, 2025 | -6,119.28% |
| Jun 30, 2025 | -97.54% |
| Mar 31, 2025 | -460.28% |
| Dec 31, 2024 | -344.19% |
| Sep 30, 2024 | 21.52% |
| Jun 30, 2024 | -10,416.85% |
| Mar 31, 2024 | -10,712.27% |
| Dec 31, 2023 | -3,039.13% |
| Sep 30, 2023 | -1,132.24% |
| Jun 30, 2023 | -1,807.93% |
| Mar 31, 2023 | 11.42% |
| Dec 31, 2022 | -203.42% |
| Sep 30, 2022 | -207.46% |
| Jun 30, 2022 | -155.67% |
| Mar 31, 2022 | -160.32% |
| Dec 31, 2021 | -142.57% |
| Sep 30, 2021 | -169.58% |
| Jun 30, 2021 | -174.73% |
| Mar 31, 2021 | -176.19% |
Sangamo Therapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=SGMOQ&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "SGMOQ", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=SGMOQ&period=max&api_key=YOUR_API_KEY");
const data = await res.json();