Scilex Holding (SCLX) Operating Margin (2022 - 2026)
Scilex Holding (SCLX) recorded Operating Margin of -385.02% in Q2 2026, down 177.88 percentage points from -207.14% a year earlier and down 11.16 percentage points from the prior quarter.
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Analysis
Scilex Holding (SCLX) Operating Margin (2022 - 2026) Analysis & Trends
On a TTM basis, Scilex Holding's Operating Margin came in at -1134.81% as of Jun 30, 2026, down 916.28 percentage points year-over-year; for FY2025, it came in at -1141.94%, down 994.59 percentage points from FY2024.
- Annual Operating Margin has a five-year change of -992.29 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -147.34% in FY2024 (+78.21 pp), -225.55% in FY2023 (-92.43 pp), -133.13% in FY2022 (-18.69 pp) and -114.44% in FY2021 (+35.22 pp).
- Quarterly Operating Margin has ranged from -2295.25% in Q4 2025 to -93.31% in Q3 2022 over the past five years.
- On a year-over-year basis, Operating Margin rose in two of the last eight quarters, with an average year-over-year change of -503.27 percentage points.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 245.59 percentage points in Q3 2024, against a drop of 2104.92 percentage points in Q4 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -373.85% (Q1 2026), -2295.25% (Q4 2025) and -1766.21% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Scilex Holding | 31.02 Mn | 19.00 Mn | 3.97 Mn | -385.02% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -385.02% |
| Mar 31, 2026 | -373.85% |
| Dec 31, 2025 | -2,295.25% |
| Sep 30, 2025 | -1,766.21% |
| Jun 30, 2025 | -207.14% |
| Mar 31, 2025 | -557.51% |
| Dec 31, 2024 | -190.33% |
| Sep 30, 2024 | -137.97% |
| Jun 30, 2024 | -95.44% |
| Mar 31, 2024 | -178.96% |
| Dec 31, 2023 | -136.23% |
| Sep 30, 2023 | -383.56% |
| Jun 30, 2023 | -181.32% |
| Mar 31, 2023 | -240.72% |
| Dec 31, 2022 | -165.63% |
| Sep 30, 2022 | -93.31% |
| Jun 30, 2022 | -144.73% |
| Mar 31, 2022 | -129.27% |
API Access
Scilex Holding Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=SCLX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "SCLX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=SCLX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();