Growth Metrics

Scilex Holding (SCLX) Operating Margin (2021 - 2025)

Scilex Holding has reported Operating Margin over the past 5 years, most recently at 2317.76% for Q4 2025.

  • On a quarterly basis, Operating Margin fell 258421.0% to 2317.76% in Q4 2025 year-over-year; TTM through Dec 2025 was 1143.71%, a 111670.0% decrease, with the full-year FY2025 number at 1143.71%, down 111670.0% from a year prior.
  • Operating Margin reached 2317.76% in Q4 2025 per SCLX's latest filing, down from 1766.21% in the prior quarter.
  • The five-year high for Operating Margin was 37058.72% in Q4 2021, with the low at 2317.76% in Q4 2025.
  • The 5-year median for Operating Margin is 165.63% (2022), against an average of 1834.95%.
  • Peak YoY movement for Operating Margin: plummeted -3722434bps in 2022, then surged 63424bps in 2023.
  • Tracing SCLX's Operating Margin over 5 years: stood at 37058.72% in 2021, then tumbled by -100bps to 165.63% in 2022, then soared by 383bps to 468.62% in 2023, then plummeted by -43bps to 266.45% in 2024, then crashed by -970bps to 2317.76% in 2025.
  • According to Business Quant data, Operating Margin over the past three periods came in at 2317.76%, 1766.21%, and 207.23% for Q4 2025, Q3 2025, and Q2 2025 respectively.