Growth Metrics

Regenxbio (RGNX) Operating Margin (2016 - 2025)

Regenxbio has reported Operating Margin over the past 12 years, most recently at 189.99% for Q4 2025.

  • Quarterly results put Operating Margin at 189.99% for Q4 2025, up 5216.0% from a year ago — trailing twelve months through Dec 2025 was 94.58% (up 18546.0% YoY), and the annual figure for FY2025 was 94.58%, up 18546.0%.
  • Operating Margin for Q4 2025 was 189.99% at Regenxbio, down from 176.27% in the prior quarter.
  • Over the last five years, Operating Margin for RGNX hit a ceiling of 78.66% in Q4 2021 and a floor of 408.8% in Q1 2024.
  • Median Operating Margin over the past 5 years was 239.58% (2021), compared with a mean of 228.77%.
  • Biggest five-year swings in Operating Margin: tumbled -26297bps in 2022 and later soared 42243bps in 2025.
  • Regenxbio's Operating Margin stood at 78.66% in 2021, then tumbled by -334bps to 184.31% in 2022, then plummeted by -56bps to 287.68% in 2023, then rose by 16bps to 242.14% in 2024, then increased by 22bps to 189.99% in 2025.
  • The last three reported values for Operating Margin were 189.99% (Q4 2025), 176.27% (Q3 2025), and 296.26% (Q2 2025) per Business Quant data.