Growth Metrics

Ultragenyx Pharmaceutical (RARE) Operating Margin (2016 - 2025)

Ultragenyx Pharmaceutical (RARE) has disclosed Operating Margin for 10 consecutive years, with 145.56% as the latest value for Q4 2025.

  • Quarterly Operating Margin rose 21984.0% to 145.56% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 17.83% through Dec 2025, up 7788.0% year-over-year, with the annual reading at 17.83% for FY2025, 7788.0% up from the prior year.
  • Operating Margin for Q4 2025 was 145.56% at Ultragenyx Pharmaceutical, up from 106.85% in the prior quarter.
  • The five-year high for Operating Margin was 145.56% in Q4 2025, with the low at 248.14% in Q3 2022.
  • Average Operating Margin over 5 years is 110.82%, with a median of 108.62% recorded in 2021.
  • The sharpest move saw Operating Margin skyrocketed 22511bps in 2021, then tumbled -13812bps in 2022.
  • Over 5 years, Operating Margin stood at 122.99% in 2021, then dropped by -15bps to 140.91% in 2022, then surged by 32bps to 95.83% in 2023, then grew by 22bps to 74.28% in 2024, then surged by 296bps to 145.56% in 2025.
  • According to Business Quant data, Operating Margin over the past three periods came in at 145.56%, 106.85%, and 64.8% for Q4 2025, Q3 2025, and Q2 2025 respectively.