uniQure (QURE) Operating Margin (2016 - 2026)

uniQure (QURE) recorded quarterly Operating Margin of 1283.55% in Q1 2026, down 184.73% quarter-over-quarter from 1514.89% in Q4 2025, and up 122641.0% on a YoY basis from N/an in Q1 2025.

uniQure (QURE) Operating Margin (2016 - 2026) Analysis & Trends

uniQure's Operating Margin history runs 11 years deep, the most recent figure standing at 1283.55% for Q1 2026.

  • In Q1 2026, Operating Margin rose 122641.0% year-over-year to 1283.55%; the TTM figure through Mar 2026 stood at 311.01% (up 52755.0% YoY), while the FY2025 annual figure was 309.86%, up 36971.0% from the prior year.
  • Operating Margin was 1283.55% for Q1 2026 at uniQure, down from 1514.89% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 2123.35% in Q4 2023 to a low of 11279.88% in Q2 2022.
  • Historically, Operating Margin has averaged 2018.69% across 5 years, with a median of 1378.95% in 2025.
  • The sharpest annual moves came in 2022 and 2023: Operating Margin plunged 1136568 bps in 2022, then surged 859309 bps in 2023.
  • A 5-year view of Operating Margin shows it stood at 25.79% in 2022, then surged by 8132 bps to 2123.35% in 2023, then plunged by 141 bps to 877.76% in 2024, then soared by 273 bps to 1514.89% in 2025, then sank by 185 bps to 1283.55% in 2026.
  • The last three Operating Margin figures came in at 1283.55% (Q1 2026), 1514.89% (Q4 2025), and 1378.95% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 uniQure 2.88 Bn 2.88 Bn 3.34 Mn -1,283.55%

Historic Data

Download Data
DateValue
Mar 31, 2026 -1,283.55%
Dec 31, 2025 1,514.89%
Sep 30, 2025 -1,378.95%
Jun 30, 2025 -833.62%
Mar 31, 2025 -2,509.96%
Dec 31, 2024 -877.76%
Sep 30, 2024 -1,758.99%
Jun 30, 2024 -395.56%
Mar 31, 2024 -639.10%
Dec 31, 2023 2,123.35%
Sep 30, 2023 -5,819.26%
Jun 30, 2023 -2,686.79%
Mar 31, 2023 -1,392.90%
Dec 31, 2022 25.79%
Sep 30, 2022 -4,107.52%
Jun 30, 2022 -11,279.88%
Mar 31, 2022 -3,017.86%
Dec 31, 2021 -390.61%
Sep 30, 2021 -2,262.44%
Jun 30, 2021 85.80%