uniQure (QURE) Operating Margin (2016 - 2026)
uniQure (QURE) recorded quarterly Operating Margin of 1283.55% in Q1 2026, down 184.73% quarter-over-quarter from 1514.89% in Q4 2025, and up 122641.0% on a YoY basis from N/an in Q1 2025.
uniQure (QURE) Operating Margin (2016 - 2026) Analysis & Trends
uniQure's Operating Margin history runs 11 years deep, the most recent figure standing at 1283.55% for Q1 2026.
- In Q1 2026, Operating Margin rose 122641.0% year-over-year to 1283.55%; the TTM figure through Mar 2026 stood at 311.01% (up 52755.0% YoY), while the FY2025 annual figure was 309.86%, up 36971.0% from the prior year.
- Operating Margin was 1283.55% for Q1 2026 at uniQure, down from 1514.89% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 2123.35% in Q4 2023 to a low of 11279.88% in Q2 2022.
- Historically, Operating Margin has averaged 2018.69% across 5 years, with a median of 1378.95% in 2025.
- The sharpest annual moves came in 2022 and 2023: Operating Margin plunged 1136568 bps in 2022, then surged 859309 bps in 2023.
- A 5-year view of Operating Margin shows it stood at 25.79% in 2022, then surged by 8132 bps to 2123.35% in 2023, then plunged by 141 bps to 877.76% in 2024, then soared by 273 bps to 1514.89% in 2025, then sank by 185 bps to 1283.55% in 2026.
- The last three Operating Margin figures came in at 1283.55% (Q1 2026), 1514.89% (Q4 2025), and 1378.95% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | uniQure | 2.88 Bn | 2.88 Bn | 3.34 Mn | -1,283.55% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1,283.55% |
| Dec 31, 2025 | 1,514.89% |
| Sep 30, 2025 | -1,378.95% |
| Jun 30, 2025 | -833.62% |
| Mar 31, 2025 | -2,509.96% |
| Dec 31, 2024 | -877.76% |
| Sep 30, 2024 | -1,758.99% |
| Jun 30, 2024 | -395.56% |
| Mar 31, 2024 | -639.10% |
| Dec 31, 2023 | 2,123.35% |
| Sep 30, 2023 | -5,819.26% |
| Jun 30, 2023 | -2,686.79% |
| Mar 31, 2023 | -1,392.90% |
| Dec 31, 2022 | 25.79% |
| Sep 30, 2022 | -4,107.52% |
| Jun 30, 2022 | -11,279.88% |
| Mar 31, 2022 | -3,017.86% |
| Dec 31, 2021 | -390.61% |
| Sep 30, 2021 | -2,262.44% |
| Jun 30, 2021 | 85.80% |