Pyxis Oncology PYXS
NASDAQ PYXS
$3.12 -0.25 (-7.42%)
At close: Aug 20, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) Share-based Compensation (2020 - 2026)

Pyxis Oncology (PYXS) posted quarterly Share-based Compensation of -$9.6 million for Q4 2025, down 445.15% year-over-year from $2.8 million in Q4 2024, and down 247.25% quarter-over-quarter from $6.5 million in Q3 2025.

Pyxis Oncology (PYXS) Share-based Compensation (2020 - 2026) Analysis & Trends

Pyxis Oncology (PYXS) has reported Share-based Compensation for 6 consecutive years, with -$9.6 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Share-based Compensation fell 445.15% year-over-year to -$9.6 million; the TTM figure through Dec 2025 stood at $6.0 million (down 69.81% YoY), while the FY2025 annual figure was $6.0 million, down 53.65% from the prior year.
  • Share-based Compensation retreated to -$9.6 million in Q4 2025 per PYXS's latest filing, from $6.5 million in the prior quarter.
  • Across five years, Share-based Compensation topped out at $11.0 million in Q1 2025 and bottomed at -$9.6 million in Q4 2025.
  • Historically, Share-based Compensation has averaged $3.6 million across 5 years, with a median of $3.3 million in 2022.
  • Annual changes were most pronounced in 2021 — Share-based Compensation jumped 27763.64% — and 2025, when it slumped 445.15%.
  • Pyxis Oncology's Share-based Compensation stood at $3.0 million in 2021, then increased by 28.1% to $3.9 million in 2022, then declined by 17.52% to $3.2 million in 2023, then slipped by 13.75% to $2.8 million in 2024, then plunged by 445.15% to -$9.6 million in 2025.
  • Business Quant data shows PYXS's Share-based Compensation at -$9.6 million in Q4 2025, $6.5 million in Q3 2025, and $8.3 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Stock Comp. (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 108.10 Mn
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 243.00 Mn
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn -
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn 120.00 Mn
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 137.41 Mn
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 86.63 Mn
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn 41.25 Mn
8 Royalty Pharma 26.98 Bn 26.14 Bn - -
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn 28.05 Mn
10 Pyxis Oncology 199.01 Mn 166.02 Mn - 5.80 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 5.80 Mn
Jun 30, 2026 5.80 Mn
Dec 31, 2025 -9.57 Mn
Dec 31, 2025 -9.57 Mn
Sep 30, 2025 6.50 Mn
Sep 30, 2025 6.50 Mn
Jun 30, 2025 8.30 Mn
Jun 30, 2025 8.30 Mn
Mar 31, 2025 11.00 Mn
Mar 31, 2025 11.00 Mn
Dec 31, 2024 2.77 Mn
Dec 31, 2024 2.77 Mn
Sep 30, 2024 9.93 Mn
Sep 30, 2024 9.93 Mn
Jun 30, 2024 2.87 Mn
Jun 30, 2024 2.87 Mn
Mar 31, 2024 4.32 Mn
Mar 31, 2024 4.32 Mn
Dec 31, 2023 3.22 Mn
Dec 31, 2023 3.22 Mn