Growth Metrics

Protagonist Therapeutics (PTGX) Operating Margin: 2017-2025

Historic Operating Margin for Protagonist Therapeutics (PTGX) over the last 6 years, with Sep 2025 value amounting to -985.17%.

  • Protagonist Therapeutics' Operating Margin fell 9847.00% to -985.17% in Q3 2025 from the same period last year, while for Sep 2025 it was 9.34%, marking a year-over-year decrease of 3818.00%. This contributed to the annual value of 58.20% for FY2024, which is 21429.00% up from last year.
  • As of Q3 2025, Protagonist Therapeutics' Operating Margin stood at -985.17%, which was down 29.96% from -758.04% recorded in Q2 2025.
  • In the past 5 years, Protagonist Therapeutics' Operating Margin ranged from a high of 192,189.47% in Q4 2022 and a low of -4,604.78% during Q2 2022.
  • Over the past 3 years, Protagonist Therapeutics' median Operating Margin value was -413.11% (recorded in 2025), while the average stood at -428.15%.
  • As far as peak fluctuations go, Protagonist Therapeutics' Operating Margin skyrocketed by 19,261,904bps in 2022, and later tumbled by 19,214,338bps in 2023.
  • Protagonist Therapeutics' Operating Margin (Quarterly) stood at -429.57% in 2021, then spiked by 19,261,904bps to 192,189.47% in 2022, then tumbled by 19,214,338bps to 46.10% in 2023, then surged by 3,074bps to 76.84% in 2024, then tumbled by 9,847bps to -985.17% in 2025.
  • Its last three reported values are -985.17% in Q3 2025, -758.04% for Q2 2025, and -68.18% during Q1 2025.