Growth Metrics

Opko Health (OPK) Operating Margin (2016 - 2025)

Opko Health (OPK) has disclosed Operating Margin for 16 consecutive years, with 19.13% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Operating Margin rose 3718.0% year-over-year to 19.13%, compared with a TTM value of 8.35% through Dec 2025, up 1863.0%, and an annual FY2025 reading of 8.35%, up 1297.0% over the prior year.
  • Operating Margin was 19.13% for Q4 2025 at Opko Health, down from 31.68% in the prior quarter.
  • Across five years, Operating Margin topped out at 3782.6% in Q3 2021 and bottomed at 1223.76% in Q1 2023.
  • Average Operating Margin over 5 years is 118.38%, with a median of 16.14% recorded in 2023.
  • The sharpest move saw Operating Margin surged 377747bps in 2021, then tumbled -383146bps in 2022.
  • Year by year, Operating Margin stood at 15.72% in 2021, then soared by 143bps to 6.77% in 2022, then crashed by -344bps to 16.56% in 2023, then dropped by -9bps to 18.05% in 2024, then soared by 206bps to 19.13% in 2025.
  • Business Quant data shows Operating Margin for OPK at 19.13% in Q4 2025, 31.68% in Q3 2025, and 38.25% in Q2 2025.