Northwest Biotherapeutics (NWBO) Operating Margin (2010 - 2026)
Northwest Biotherapeutics (NWBO) recorded Operating Margin of -1438.04% in Q2 2026, up 9843.64 percentage points from -11281.68% a year earlier and up 768.44 percentage points from the prior quarter.
Northwest Biotherapeutics (NWBO) Operating Margin (2010 - 2026) Analysis & Trends
On a TTM basis, Northwest Biotherapeutics' Operating Margin came in at -2316.11% as of Jun 30, 2026, up 3661.04 percentage points year-over-year; for FY2025, it was -4347.90%, up 464.55 percentage points from FY2024.
- Annual Operating Margin has a five-year change of +2360.47 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -4812.45% in FY2024 (-1939.36 pp), -2873.08% in FY2023 (+1118.66 pp), -3991.74% in FY2022 (+1252.24 pp) and -5243.98% in FY2021 (+1464.39 pp).
- The Q2 2026 figure is the highest quarterly Operating Margin since Q1 2020.
- On a year-over-year basis, Operating Margin has increased for three consecutive quarters, with an average year-over-year change of +370.23 percentage points over the last eight quarters.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 19294.13 percentage points in Q3 2021, against a drop of 7857.37 percentage points in Q2 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -2206.48% (Q1 2026), -2009.52% (Q4 2025) and -7160.00% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Northwest Biotherapeutics | 250.40 Mn | 240.41 Mn | - | -1,438.04% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,438.04% |
| Mar 31, 2026 | -2,206.48% |
| Dec 31, 2025 | -2,009.52% |
| Sep 30, 2025 | -7,160.00% |
| Jun 30, 2025 | -11,281.68% |
| Mar 31, 2025 | -4,616.27% |
| Dec 31, 2024 | -8,008.23% |
| Sep 30, 2024 | -4,145.94% |
| Jun 30, 2024 | -3,424.31% |
| Mar 31, 2024 | -5,543.66% |
| Dec 31, 2023 | -3,402.70% |
| Sep 30, 2023 | -3,405.17% |
| Jun 30, 2023 | -6,754.73% |
| Mar 31, 2023 | -1,473.18% |
| Dec 31, 2022 | -3,044.89% |
| Sep 30, 2022 | -7,581.55% |
| Jun 30, 2022 | -4,423.27% |
| Mar 31, 2022 | -3,048.64% |
| Sep 30, 2021 | -2,871.14% |
| Jun 30, 2021 | -2,982.45% |
Northwest Biotherapeutics Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=NWBO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "NWBO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=NWBO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();