Neurocrine Biosciences (NBIX) Operating Margin (2010 - 2026)

Neurocrine Biosciences (NBIX) posted Operating Margin of 23.74% for Q1 2026, down 9.31% on a QoQ basis from 26.18% in Q4 2025, and up 1962.0% year-over-year from 1.15% in Q1 2025.

Neurocrine Biosciences (NBIX) Operating Margin (2010 - 2026) Analysis & Trends

Neurocrine Biosciences' Operating Margin history runs 16 years deep, the most recent figure standing at 23.74% for Q1 2026.

  • Quarterly Operating Margin rose 1962.0% year-over-year to 23.74% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 25.43% (up 492.0% YoY) and the FY2025 annual result came in at 21.64%, down 258.0% from the prior year.
  • Operating Margin was 23.74% for Q1 2026 at Neurocrine Biosciences, down from 26.18% in the prior quarter.
  • Across five years, Operating Margin topped out at 273.5% in Q2 2022 and bottomed at 27.16% in Q1 2023.
  • A 5-year average of 33.54% and a median of 23.74% in 2026 frame the typical range for Operating Margin.
  • Annual changes were most pronounced in 2022 — Operating Margin jumped 25176 bps — and 2023, when it sank 25724 bps.
  • Neurocrine Biosciences' Operating Margin stood at 25.1% in 2022, then increased by 16 bps to 29.17% in 2023, then dropped by 22 bps to 22.62% in 2024, then increased by 16 bps to 26.18% in 2025, then retreated by 9 bps to 23.74% in 2026.
  • Business Quant data shows NBIX's Operating Margin at 23.74% in Q1 2026, 26.18% in Q4 2025, and 30.07% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn 16.37%
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn 36.83%
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn -38.02%
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn 41.69%
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn -2.27%
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn 23.74%
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn 21.23%
10 Vireo Growth 10.57 Bn 10.41 Bn 59.30 Mn 8.47%

Historic Data

Download Data
DateValue
Mar 31, 2026 23.74%
Dec 31, 2025 26.18%
Sep 30, 2025 30.07%
Jun 30, 2025 21.18%
Mar 31, 2025 4.12%
Dec 31, 2024 22.62%
Sep 30, 2024 29.55%
Jun 30, 2024 24.64%
Mar 31, 2024 19.27%
Dec 31, 2023 29.17%
Sep 30, 2023 28.31%
Jun 30, 2023 16.26%
Mar 31, 2023 -27.16%
Dec 31, 2022 25.10%
Sep 30, 2022 22.63%
Jun 30, 2022 273.50%
Mar 31, 2022 1.00%
Dec 31, 2021 -11.63%
Sep 30, 2021 15.03%
Jun 30, 2021 21.74%