Growth Metrics

Neurocrine Biosciences (NBIX) Operating Margin (2017 - 2026)

Neurocrine Biosciences filings provide 15 years of Operating Margin readings, the most recent being 26.18% for Q4 2025.

  • On a quarterly basis, Operating Margin rose 356.0% to 26.18% in Q4 2025 year-over-year; TTM through Dec 2025 was 21.64%, a 258.0% decrease, with the full-year FY2025 number at 21.64%, down 258.0% from a year prior.
  • Operating Margin hit 26.18% in Q4 2025 for Neurocrine Biosciences, down from 30.07% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 273.5% in Q2 2022 to a low of 27.16% in Q1 2023.
  • Median Operating Margin over the past 5 years was 22.18% (2021), compared with a mean of 29.24%.
  • Biggest five-year swings in Operating Margin: soared 25176bps in 2022 and later crashed -25724bps in 2023.
  • Neurocrine Biosciences' Operating Margin stood at 11.63% in 2021, then skyrocketed by 316bps to 25.1% in 2022, then increased by 16bps to 29.17% in 2023, then dropped by -22bps to 22.62% in 2024, then increased by 16bps to 26.18% in 2025.
  • The last three reported values for Operating Margin were 26.18% (Q4 2025), 30.07% (Q3 2025), and 21.18% (Q2 2025) per Business Quant data.