Mirum Pharmaceuticals (MIRM) Operating Margin (2021 - 2026)

Mirum Pharmaceuticals' Operating Margin history runs 6 years deep, the most recent figure standing at 493.78% for Q1 2026.

• In Q1 2026, Operating Margin fell 48017.0% year-over-year to 493.78%; the TTM figure through Mar 2026 stood at 139.82% (down 11969.0% YoY), while the FY2025 annual figure was 4.25%, up 2176.0% from the prior year.
• Operating Margin for Q1 2026 stood at 493.78%, down from 3.07% in the prior quarter.
• The five-year high for Operating Margin was 1.96% in Q3 2025, with the low at 493.78% in Q1 2026.
• The 5-year median for Operating Margin is 46.85% (2023), against an average of 94.21%.
• The sharpest annual moves came in 2022 and 2026: Operating Margin surged 132994 bps in 2022, then sank 48017 bps in 2026.
• Mirum Pharmaceuticals' Operating Margin stood at 122.41% in 2022, then soared by 62 bps to 46.85% in 2023, then surged by 48 bps to 24.36% in 2024, then surged by 87 bps to 3.07% in 2025, then sank by 16002 bps to 493.78% in 2026.
• Business Quant data shows MIRM's Operating Margin at 493.78% in Q1 2026, 3.07% in Q4 2025, and 1.96% in Q3 2025.