Mirum Pharmaceuticals (MIRM) Operating Margin (2021 - 2026)
Mirum Pharmaceuticals' quarterly Operating Margin came in at 493.78% in Q1 2026, down 48017.0% year-on-year from N/an in Q1 2025, and down 16002.39% quarter-over-quarter from 3.07% in Q4 2025.
Mirum Pharmaceuticals has reported Operating Margin for 6 years, with the latest figure at 493.78% in Q1 2026.
- For the quarter ending Q1 2026, Operating Margin fell 48017.0% year-over-year to 493.78%; the trailing twelve-month figure through Mar 2026 stood at 139.82% (down 11969.0% YoY), and the FY2025 full-year result was 4.25%, up 2176.0% from the prior year.
- Operating Margin for Q1 2026 stood at 493.78%, down from 3.07% in the prior quarter.
- The five-year high for Operating Margin was 1.96% in Q3 2025, with the low at 493.78% in Q1 2026.
- Average Operating Margin over 5 years is 94.21%, with a median of 46.85% recorded in 2023.
- Year-over-year, Operating Margin surged 132994 bps in 2022 and slumped 48017 bps in 2026.
- Tracing MIRM's Operating Margin over 5 years: stood at 122.41% in 2022, then surged by 62 bps to 46.85% in 2023, then jumped by 48 bps to 24.36% in 2024, then jumped by 87 bps to 3.07% in 2025, then sank by 16002 bps to 493.78% in 2026.
- The last three Operating Margin figures came in at 493.78% (Q1 2026), 3.07% (Q4 2025), and 1.96% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 17.83% |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 23.02% |
| 10 | Mirum Pharmaceuticals | 5.97 Bn | 5.59 Bn | 131.08 Mn | -493.78% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -493.78% |
| Dec 31, 2025 | -3.07% |
| Sep 30, 2025 | 1.96% |
| Jun 30, 2025 | -3.90% |
| Mar 31, 2025 | -13.61% |
| Dec 31, 2024 | -24.36% |
| Sep 30, 2024 | -14.03% |
| Jun 30, 2024 | -31.12% |
| Mar 31, 2024 | -38.24% |
| Dec 31, 2023 | -46.85% |
| Sep 30, 2023 | -52.69% |
| Jun 30, 2023 | -64.73% |
| Mar 31, 2023 | -85.92% |
| Dec 31, 2022 | -122.41% |
| Sep 30, 2022 | -175.09% |
| Jun 30, 2022 | -179.83% |
| Mar 31, 2022 | -253.92% |
| Dec 31, 2021 | -1,452.36% |
| Sep 30, 2021 | -856.48% |
| Jun 30, 2021 | -340.01% |