MeiraGTx Holdings (MGTX) Operating Margin (2019 - 2025)
MeiraGTx Holdings' (MGTX) quarterly Operating Margin came in at 24.2% in Q4 2025, up 17142.0% YoY from N/an in Q4 2024, and up 100.22% on a QoQ basis from 11231.95% in Q3 2025.
MeiraGTx Holdings (MGTX) Operating Margin (2019 - 2025) Analysis & Trends
MeiraGTx Holdings (MGTX) has 7 years of Operating Margin data on file, last reported at 24.2% in Q4 2025.
- Quarterly Operating Margin rose 17142.0% year-over-year to 24.2% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 105.68% (up 39377.0% YoY) and the FY2025 annual result came in at 140.31%, up 35313.0% from the prior year.
- Operating Margin rose to 24.2% in Q4 2025, from 11231.95% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 776.38% in Q4 2022 to a low of 17241.13% in Q2 2024.
- A 5-year average of 2123.16% and a median of 473.59% in 2022 frame the typical range for Operating Margin.
- Annual changes were most pronounced in 2024 — Operating Margin tumbled 1642800 bps — and 2025, when it surged 1619006 bps.
- Tracing MGTX's Operating Margin over 5 years: stood at 36.54% in 2021, then jumped by 2224 bps to 776.38% in 2022, then plunged by 41 bps to 454.9% in 2023, then tumbled by 132 bps to 147.22% in 2024, then jumped by 116 bps to 24.2% in 2025.
- The last three Operating Margin figures came in at 24.2% (Q4 2025), 11231.95% (Q3 2025), and 1051.07% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 31.68% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 19.06% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -105.20% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 19.75% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 17.93% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -0.36% |
| 10 | MeiraGTx Holdings | 1.10 Bn | 1.03 Bn | - | 24.20% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 24.20% |
| Sep 30, 2025 | -11,231.95% |
| Jun 30, 2025 | -1,051.07% |
| Dec 31, 2024 | -147.22% |
| Sep 30, 2024 | -360.49% |
| Jun 30, 2024 | -17,241.13% |
| Mar 31, 2024 | -6,710.47% |
| Dec 31, 2023 | 454.90% |
| Sep 30, 2023 | -642.01% |
| Jun 30, 2023 | -813.14% |
| Mar 31, 2023 | -952.61% |
| Dec 31, 2022 | 776.38% |
| Sep 30, 2022 | -473.59% |
| Jun 30, 2022 | -220.82% |
| Mar 31, 2022 | -510.10% |
| Dec 31, 2021 | -36.54% |
| Sep 30, 2021 | -324.58% |
| Jun 30, 2021 | -400.37% |
| Mar 31, 2021 | -479.48% |
| Dec 31, 2020 | -348.94% |