Growth Metrics

Macrogenics (MGNX) Operating Margin (2016 - 2025)

Macrogenics (MGNX) has disclosed Operating Margin for 14 consecutive years, with 29.34% as the latest value for Q4 2025.

  • Quarterly Operating Margin rose 10275.0% to 29.34% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 48.72% through Dec 2025, up 1907.0% year-over-year, with the annual reading at 48.72% for FY2025, 2501.0% up from the prior year.
  • Operating Margin for Q4 2025 was 29.34% at Macrogenics, down from 25.59% in the prior quarter.
  • The five-year high for Operating Margin was 48.95% in Q3 2024, with the low at 1763.06% in Q2 2024.
  • Average Operating Margin over 5 years is 310.95%, with a median of 234.56% recorded in 2021.
  • The sharpest move saw Operating Margin tumbled -142078bps in 2024, then surged 159779bps in 2025.
  • Over 5 years, Operating Margin stood at 411.65% in 2021, then skyrocketed by 104bps to 16.39% in 2022, then plummeted by -2908bps to 460.39% in 2023, then surged by 71bps to 132.09% in 2024, then soared by 78bps to 29.34% in 2025.
  • According to Business Quant data, Operating Margin over the past three periods came in at 29.34%, 25.59%, and 165.27% for Q4 2025, Q3 2025, and Q2 2025 respectively.