Macrogenics (MGNX) Operating Margin (2012 - 2026)
Macrogenics' (MGNX) quarterly Operating Margin came in at 160.96% in Q1 2026, up 16215.0% year-on-year from N/an in Q1 2025, and down 448.55% on a QoQ basis from 29.34% in Q4 2025.
Macrogenics (MGNX) Operating Margin (2012 - 2026) Analysis & Trends
Macrogenics (MGNX) has 15 years of Operating Margin data on file, last reported at 160.96% in Q1 2026.
- On a quarterly basis, Operating Margin rose 16215.0% year-over-year to 160.96% in Q1 2026; TTM through Mar 2026 was 40.53%, a 1640.0% increase from a year earlier, with the FY2025 full-year figure at 48.72%, up 2501.0% from the prior year.
- Operating Margin for Q1 2026 stood at 160.96%, down from 29.34% in the prior quarter.
- Over the last five years, Operating Margin for MGNX reached as high as 48.95% in Q3 2024 and fell as low as 600.29% in Q1 2022.
- Historically, Operating Margin has averaged 233.59% across 5 years, with a median of 160.96% in 2026.
- On a YoY basis, Operating Margin climbed as much as 44342 bps in 2023 and fell as far as 47678 bps in 2023.
- Year by year, Operating Margin stood at 16.39% in 2022, then slumped by 2908 bps to 460.39% in 2023, then soared by 71 bps to 132.09% in 2024, then jumped by 78 bps to 29.34% in 2025, then slumped by 449 bps to 160.96% in 2026.
- Per Business Quant data, the three most recent Operating Margin figures were 160.96% in Q1 2026, 29.34% in Q4 2025, and 25.59% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Macrogenics | 254.43 Mn | 187.92 Mn | - | -160.96% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -160.96% |
| Dec 31, 2025 | -29.34% |
| Sep 30, 2025 | 25.59% |
| Jun 30, 2025 | -165.27% |
| Mar 31, 2025 | -323.10% |
| Dec 31, 2024 | -132.09% |
| Sep 30, 2024 | 48.95% |
| Jun 30, 2024 | -538.86% |
| Mar 31, 2024 | -590.40% |
| Dec 31, 2023 | -460.39% |
| Sep 30, 2023 | -341.46% |
| Jun 30, 2023 | -342.28% |
| Mar 31, 2023 | -156.87% |
| Dec 31, 2022 | 16.39% |
| Sep 30, 2022 | -59.80% |
| Jun 30, 2022 | -160.76% |
| Mar 31, 2022 | -600.29% |
| Dec 31, 2021 | -411.65% |
| Sep 30, 2021 | -338.32% |
| Jun 30, 2021 | -130.96% |