Vertex Pharmaceuticals VRTX
NASDAQ VRTX
$546.12 -11.84 (-2.12%)
At close: Sep 4, 2026 · 4:00 PM EDT

Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026)

Vertex Pharmaceuticals (VRTX) posted Change in Cash of $649.2 million for Q2 2026, up 55.65% on a QoQ basis from $417.1 million in Q1 2026, and up 118.88% year-over-year from $296.6 million in Q2 2025.

Analysis

Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals has reported Change in Cash for 18 years, with the latest figure at $649.2 million in Q2 2026.

  • On a quarterly basis, Change in Cash rose 118.88% year-over-year to $649.2 million in Q2 2026; TTM through Jun 2026 was $1.2 billion, a 199.77% increase from a year earlier, with the FY2025 full-year figure at $515.6 million, up 108.89% from the prior year.
  • Change in Cash was $649.2 million for Q2 2026 at Vertex Pharmaceuticals, up from $417.1 million in the prior quarter.
  • The five-year high for Change in Cash was $1.3 billion in Q4 2022, with the low at -$4.6 billion in Q2 2024.
  • Average Change in Cash over 5 years is -$35.9 million, with a median of $356.8 million recorded in 2025.
  • The sharpest annual moves came in 2022 and 2024: Change in Cash soared 554.96% in 2022, then plunged 633.74% in 2024.
  • Over 5 years, Change in Cash stood at $1.3 billion in 2022, then sank by 155.75% to -$744.3 million in 2023, then climbed by 9.19% to -$675.9 million in 2024, then soared by 120.71% to $140.0 million in 2025, then jumped by 363.71% to $649.2 million in 2026.
  • The last three Change in Cash figures came in at $649.2 million (Q2 2026), $417.1 million (Q1 2026), and $140.0 million (Q4 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Amgen 236.37 Bn 222.38 Bn 7.24 Bn 1.95 Bn
2 Gilead Sciences 187.38 Bn 184.12 Bn 6.22 Bn -4.45 Bn
3 Vertex Pharmaceuticals 138.36 Bn 130.51 Bn 2.84 Bn 649.20 Mn
4 Regeneron Pharmaceuticals 85.09 Bn 77.10 Bn 3.93 Bn -504.60 Mn
5 Argenx Se 63.93 Bn 58.75 Bn 1.37 Bn -
6 Moderna 58.07 Bn 52.94 Bn 52.00 Mn -185.00 Mn
7 Alnylam Pharmaceuticals 35.59 Bn 32.28 Bn 992.69 Mn -2.94 Mn
8 Biogen 32.63 Bn 31.34 Bn 1.96 Bn -2.09 Bn
9 Insmed 27.57 Bn 26.41 Bn 358.27 Mn -37.42 Mn
10 BioNTech SE 26.24 Bn 12.58 Bn 10.00 Mn -230.26 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 649.20 Mn
Mar 31, 2026 417.10 Mn
Dec 31, 2025 140.00 Mn
Sep 30, 2025 -34.20 Mn
Jun 30, 2025 296.60 Mn
Mar 31, 2025 113.20 Mn
Dec 31, 2024 -675.90 Mn
Sep 30, 2024 657.10 Mn
Jun 30, 2024 -4.58 Bn
Mar 31, 2024 -1.20 Bn
Dec 31, 2023 -744.30 Mn
Sep 30, 2023 963.20 Mn
Jun 30, 2023 857.80 Mn
Mar 31, 2023 -1.22 Bn
Dec 31, 2022 1.34 Bn
Sep 30, 2022 472.90 Mn
Jun 30, 2022 1.10 Bn
Mar 31, 2022 803.90 Mn
Dec 31, 2021 519.90 Mn
Sep 30, 2021 209.10 Mn