Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026)
Vertex Pharmaceuticals' quarterly Change in Cash came in at $417.1 million in Q1 2026, up 268.46% year-on-year from $113.2 million in Q1 2025, and up 197.93% quarter-over-quarter from $140.0 million in Q4 2025.
Vertex Pharmaceuticals has reported Change in Cash for 18 years, with the latest figure at $417.1 million in Q1 2026.
- For the quarter ending Q1 2026, Change in Cash rose 268.46% year-over-year to $417.1 million; the trailing twelve-month figure through Mar 2026 stood at $819.5 million (up 118.28% YoY), and the FY2025 full-year result was $515.6 million, up 108.89% from the prior year.
- Change in Cash for Q1 2026 stood at $417.1 million, up from $140.0 million in the prior quarter.
- The five-year high for Change in Cash was $1.3 billion in Q4 2022, with the low at -$4.6 billion in Q2 2024.
- Average Change in Cash over 5 years is -$76.2 million, with a median of $296.6 million recorded in 2025.
- Year-over-year, Change in Cash jumped 554.96% in 2022 and sank 633.74% in 2024.
- Tracing VRTX's Change in Cash over 5 years: stood at $1.3 billion in 2022, then sank by 155.75% to -$744.3 million in 2023, then climbed by 9.19% to -$675.9 million in 2024, then soared by 120.71% to $140.0 million in 2025, then jumped by 197.93% to $417.1 million in 2026.
- The last three Change in Cash figures came in at $417.1 million (Q1 2026), $140.0 million (Q4 2025), and -$34.2 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 623.00 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 417.10 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | -153.10 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 53.61 Mn |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | 57.19 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 417.10 Mn |
| Dec 31, 2025 | 140.00 Mn |
| Sep 30, 2025 | -34.20 Mn |
| Jun 30, 2025 | 296.60 Mn |
| Mar 31, 2025 | 113.20 Mn |
| Dec 31, 2024 | -675.90 Mn |
| Sep 30, 2024 | 657.10 Mn |
| Jun 30, 2024 | -4.58 Bn |
| Mar 31, 2024 | -1.20 Bn |
| Dec 31, 2023 | -744.30 Mn |
| Sep 30, 2023 | 963.20 Mn |
| Jun 30, 2023 | 857.80 Mn |
| Mar 31, 2023 | -1.22 Bn |
| Dec 31, 2022 | 1.34 Bn |
| Sep 30, 2022 | 472.90 Mn |
| Jun 30, 2022 | 1.10 Bn |
| Mar 31, 2022 | 803.90 Mn |
| Dec 31, 2021 | 519.90 Mn |
| Sep 30, 2021 | 209.10 Mn |
| Jun 30, 2021 | -241.80 Mn |
| Mar 31, 2021 | 324.00 Mn |
| Dec 31, 2020 | 627.90 Mn |
| Sep 30, 2020 | 525.29 Mn |
| Jun 30, 2020 | 1.23 Bn |
| Mar 31, 2020 | 481.28 Mn |
| Dec 31, 2019 | -283.94 Mn |
| Sep 30, 2019 | 102.95 Mn |
| Jun 30, 2019 | 400.11 Mn |
| Mar 31, 2019 | 243.28 Mn |
| Dec 31, 2018 | 171.20 Mn |
| Sep 30, 2018 | 332.98 Mn |
| Jun 30, 2018 | 148.34 Mn |
| Mar 31, 2018 | 338.20 Mn |
| Dec 31, 2017 | 280.76 Mn |
| Sep 30, 2017 | 99.01 Mn |
| Jun 30, 2017 | 239.52 Mn |
| Mar 31, 2017 | -183.46 Mn |
| Dec 31, 2016 | 411.02 Mn |
| Sep 30, 2016 | 113.83 Mn |
| Jun 30, 2016 | 1.62 Mn |
| Mar 31, 2016 | -110.52 Mn |
| Dec 31, 2015 | -41.48 Mn |
| Sep 30, 2015 | -114.29 Mn |
| Jun 30, 2015 | 205.66 Mn |
| Mar 31, 2015 | 39.62 Mn |
| Dec 31, 2014 | -93.30 Mn |
| Sep 30, 2014 | 298.01 Mn |
| Jun 30, 2014 | -3.49 Mn |
| Mar 31, 2014 | -145.25 Mn |
| Dec 31, 2013 | -13.88 Mn |
| Sep 30, 2013 | 51.93 Mn |
| Jun 30, 2013 | 152.15 Mn |
| Mar 31, 2013 | -110.31 Mn |
| Dec 31, 2012 | 52.52 Mn |
| Sep 30, 2012 | -17.18 Mn |
| Jun 30, 2012 | 186.14 Mn |
| Mar 31, 2012 | -207.40 Mn |
| Dec 31, 2011 | -67.23 Mn |
| Sep 30, 2011 | 84.35 Mn |
| Mar 31, 2011 | 203.34 Mn |
| Dec 31, 2010 | -326.70 Mn |
| Sep 30, 2010 | 232.29 Mn |
| Jun 30, 2010 | -58.94 Mn |
| Mar 31, 2010 | -50.11 Mn |
| Dec 31, 2009 | -112.48 Mn |
| Sep 30, 2009 | 150.18 Mn |
| Jun 30, 2009 | -193.25 Mn |
| Mar 31, 2009 | 213.08 Mn |