Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026)
Vertex Pharmaceuticals' (VRTX) quarterly Change in Cash came in at $417.1 million in Q1 2026, up 268.46% year-on-year from $113.2 million in Q1 2025, and up 197.93% quarter-over-quarter from $140.0 million in Q4 2025.
Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Change in Cash history runs 18 years deep, the most recent figure standing at $417.1 million for Q1 2026.
- On a quarterly basis, Change in Cash rose 268.46% year-over-year to $417.1 million in Q1 2026; TTM through Mar 2026 was $819.5 million, a 118.28% increase from a year earlier, with the FY2025 full-year figure at $515.6 million, up 108.89% from the prior year.
- Change in Cash rose to $417.1 million in Q1 2026 per VRTX's latest filing, from $140.0 million in the prior quarter.
- Across five years, Change in Cash topped out at $1.3 billion in Q4 2022 and bottomed at -$4.6 billion in Q2 2024.
- The 5-year median for Change in Cash is $296.6 million (2025), against an average of -$76.2 million.
- Across the five-year window, Change in Cash jumped 554.96% in 2022 and sank 633.74% in 2024, its largest moves.
- Year by year, Change in Cash stood at $1.3 billion in 2022, then plunged by 155.75% to -$744.3 million in 2023, then advanced by 9.19% to -$675.9 million in 2024, then surged by 120.71% to $140.0 million in 2025, then soared by 197.93% to $417.1 million in 2026.
- Per Business Quant, the three latest VRTX Change in Cash figures stand at $417.1 million (Q1 2026), $140.0 million (Q4 2025), and -$34.2 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -22.03 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -2.44 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 243.78 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 417.10 Mn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | -153.10 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 57.19 Mn |
| 10 | Alnylam Pharmaceuticals | 36.08 Bn | 33.07 Bn | 959.66 Mn | 53.61 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 417.10 Mn |
| Dec 31, 2025 | 140.00 Mn |
| Sep 30, 2025 | -34.20 Mn |
| Jun 30, 2025 | 296.60 Mn |
| Mar 31, 2025 | 113.20 Mn |
| Dec 31, 2024 | -675.90 Mn |
| Sep 30, 2024 | 657.10 Mn |
| Jun 30, 2024 | -4.58 Bn |
| Mar 31, 2024 | -1.20 Bn |
| Dec 31, 2023 | -744.30 Mn |
| Sep 30, 2023 | 963.20 Mn |
| Jun 30, 2023 | 857.80 Mn |
| Mar 31, 2023 | -1.22 Bn |
| Dec 31, 2022 | 1.34 Bn |
| Sep 30, 2022 | 472.90 Mn |
| Jun 30, 2022 | 1.10 Bn |
| Mar 31, 2022 | 803.90 Mn |
| Dec 31, 2021 | 519.90 Mn |
| Sep 30, 2021 | 209.10 Mn |
| Jun 30, 2021 | -241.80 Mn |