Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026)
Vertex Pharmaceuticals' Change in Cash came in at -$1.17 billion for Q3 2026, compared with -$34.2 million a year earlier.
Powered by 
Analysis
Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026) Analysis & Trends
Over the trailing twelve months to Sep 30, 2026, Vertex Pharmaceuticals reported Change in Cash of $40.8 million; for FY2025, it came in at $515.6 million.
- Change in Cash carries a five-year compound annual growth rate of -29.1% (FY2020 to FY2025).
- Going back by year, Change in Cash was -$5.8 billion in FY2024, -$139.7 million in FY2023, $3.71 billion in FY2022 (+357.6%) and $811.2 million in FY2021 (-71.7%).
- The Q3 2026 figure represents the lowest quarterly Change in Cash since Q2 2024.
- The fastest year-over-year change in Change in Cash over five years came in Q1 2026 (growth of 268.5%), and the weakest in Q3 2024 (a decline of 31.8%).
- Business Quant data shows VRTX's Change in Cash at $649.2 million (Q2 2026), $417.1 million (Q1 2026) and $140 million (Q4 2025) in the three quarters before Q3 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,359.75 Bn | 1,333.37 Bn | 20.46 Bn | -4.07 Bn |
| 2 | Johnson & Johnson | 688.76 Bn | 608.62 Bn | 17.30 Bn | -3.51 Bn |
| 3 | AbbVie | 521.69 Bn | 489.75 Bn | 13.12 Bn | 4.21 Bn |
| 4 | Merck | 364.31 Bn | 327.31 Bn | 13.19 Bn | 2.76 Bn |
| 5 | Novartis Ag | 306.35 Bn | 279.93 Bn | - | - |
| 6 | Astrazeneca | 285.96 Bn | 259.56 Bn | 13.26 Bn | 3.04 Bn |
| 7 | Amgen | 251.88 Bn | 203.53 Bn | 7.58 Bn | -799.00 Mn |
| 8 | Gilead Sciences | 208.59 Bn | 183.61 Bn | 6.73 Bn | 3.26 Bn |
| 9 | Pfizer | 164.73 Bn | 112.38 Bn | 12.56 Bn | 845.00 Mn |
| 10 | Vertex Pharmaceuticals | 136.55 Bn | 104.28 Bn | 2.91 Bn | -1.17 Bn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -1.17 Bn |
| Jun 30, 2026 | 649.20 Mn |
| Mar 31, 2026 | 417.10 Mn |
| Dec 31, 2025 | 140.00 Mn |
| Sep 30, 2025 | -34.20 Mn |
| Jun 30, 2025 | 296.60 Mn |
| Mar 31, 2025 | 113.20 Mn |
| Dec 31, 2024 | -675.90 Mn |
| Sep 30, 2024 | 657.10 Mn |
| Jun 30, 2024 | -4.58 Bn |
| Mar 31, 2024 | -1.20 Bn |
| Dec 31, 2023 | -744.30 Mn |
| Sep 30, 2023 | 963.20 Mn |
| Jun 30, 2023 | 857.80 Mn |
| Mar 31, 2023 | -1.22 Bn |
| Dec 31, 2022 | 1.34 Bn |
| Sep 30, 2022 | 472.90 Mn |
| Jun 30, 2022 | 1.10 Bn |
| Mar 31, 2022 | 803.90 Mn |
| Dec 31, 2021 | 519.90 Mn |
API Access
Vertex Pharmaceuticals Change in Cash API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=change-in-cash&ticker=VRTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "change-in-cash", "ticker": "VRTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=change-in-cash&ticker=VRTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();