Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026)
Vertex Pharmaceuticals (VRTX) posted quarterly Change in Cash of $417.1 million for Q1 2026, up 268.46% year-over-year from $113.2 million in Q1 2025, and up 197.93% quarter-over-quarter from $140.0 million in Q4 2025.
Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Change in Cash history runs 18 years deep, the most recent figure standing at $417.1 million for Q1 2026.
- In Q1 2026, Change in Cash rose 268.46% year-over-year to $417.1 million; the TTM figure through Mar 2026 stood at $819.5 million (up 118.28% YoY), while the FY2025 annual figure was $515.6 million, up 108.89% from the prior year.
- Change in Cash for Q1 2026 stood at $417.1 million, up from $140.0 million in the prior quarter.
- The five-year high for Change in Cash was $1.3 billion in Q4 2022, with the low at -$4.6 billion in Q2 2024.
- The 5-year median for Change in Cash is $296.6 million (2025), against an average of -$76.2 million.
- The sharpest annual moves came in 2022 and 2024: Change in Cash jumped 554.96% in 2022, then plunged 633.74% in 2024.
- Vertex Pharmaceuticals' Change in Cash stood at $1.3 billion in 2022, then sank by 155.75% to -$744.3 million in 2023, then gained by 9.19% to -$675.9 million in 2024, then jumped by 120.71% to $140.0 million in 2025, then surged by 197.93% to $417.1 million in 2026.
- Business Quant data shows VRTX's Change in Cash at $417.1 million in Q1 2026, $140.0 million in Q4 2025, and -$34.2 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 374.50 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 427.25 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -1.97 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 225.59 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -2.94 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Roivant Sciences | 26.16 Bn | 26.85 Bn | 1.16 Mn | -170.44 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 649.20 Mn |
| Mar 31, 2026 | 417.10 Mn |
| Dec 31, 2025 | 140.00 Mn |
| Sep 30, 2025 | -34.20 Mn |
| Jun 30, 2025 | 296.60 Mn |
| Mar 31, 2025 | 113.20 Mn |
| Dec 31, 2024 | -675.90 Mn |
| Sep 30, 2024 | 657.10 Mn |
| Jun 30, 2024 | -4.58 Bn |
| Mar 31, 2024 | -1.20 Bn |
| Dec 31, 2023 | -744.30 Mn |
| Sep 30, 2023 | 963.20 Mn |
| Jun 30, 2023 | 857.80 Mn |
| Mar 31, 2023 | -1.22 Bn |
| Dec 31, 2022 | 1.34 Bn |
| Sep 30, 2022 | 472.90 Mn |
| Jun 30, 2022 | 1.10 Bn |
| Mar 31, 2022 | 803.90 Mn |
| Dec 31, 2021 | 519.90 Mn |
| Sep 30, 2021 | 209.10 Mn |