Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026)
Vertex Pharmaceuticals (VRTX) recorded quarterly Change in Cash of $417.1 million in Q1 2026, up 197.93% quarter-over-quarter from $140.0 million in Q4 2025, and up 268.46% on a YoY basis from $113.2 million in Q1 2025.
Vertex Pharmaceuticals (VRTX) Change in Cash (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Change in Cash history runs 18 years deep, the most recent figure standing at $417.1 million for Q1 2026.
- In Q1 2026, Change in Cash rose 268.46% year-over-year to $417.1 million; the TTM figure through Mar 2026 stood at $819.5 million (up 118.28% YoY), while the FY2025 annual figure was $515.6 million, up 108.89% from the prior year.
- Change in Cash was $417.1 million for Q1 2026 at Vertex Pharmaceuticals, up from $140.0 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $1.3 billion in Q4 2022 to a low of -$4.6 billion in Q2 2024.
- Historically, Change in Cash has averaged -$76.2 million across 5 years, with a median of $296.6 million in 2025.
- The sharpest annual moves came in 2022 and 2024: Change in Cash surged 554.96% in 2022, then sank 633.74% in 2024.
- A 5-year view of Change in Cash shows it stood at $1.3 billion in 2022, then slumped by 155.75% to -$744.3 million in 2023, then advanced by 9.19% to -$675.9 million in 2024, then surged by 120.71% to $140.0 million in 2025, then soared by 197.93% to $417.1 million in 2026.
- The last three Change in Cash figures came in at $417.1 million (Q1 2026), $140.0 million (Q4 2025), and -$34.2 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 623.00 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 417.10 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -45.97 Mn |
| 10 | Regeneron Pharmaceuticals | 63.43 Bn | 54.67 Bn | 3.31 Bn | -153.10 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 417.10 Mn |
| Dec 31, 2025 | 140.00 Mn |
| Sep 30, 2025 | -34.20 Mn |
| Jun 30, 2025 | 296.60 Mn |
| Mar 31, 2025 | 113.20 Mn |
| Dec 31, 2024 | -675.90 Mn |
| Sep 30, 2024 | 657.10 Mn |
| Jun 30, 2024 | -4.58 Bn |
| Mar 31, 2024 | -1.20 Bn |
| Dec 31, 2023 | -744.30 Mn |
| Sep 30, 2023 | 963.20 Mn |
| Jun 30, 2023 | 857.80 Mn |
| Mar 31, 2023 | -1.22 Bn |
| Dec 31, 2022 | 1.34 Bn |
| Sep 30, 2022 | 472.90 Mn |
| Jun 30, 2022 | 1.10 Bn |
| Mar 31, 2022 | 803.90 Mn |
| Dec 31, 2021 | 519.90 Mn |
| Sep 30, 2021 | 209.10 Mn |
| Jun 30, 2021 | -241.80 Mn |