Lexicon Pharmaceuticals (LXRX) Operating Expenses (2010 - 2026)

Lexicon Pharmaceuticals (LXRX) posted quarterly Operating Expenses of $22.1 million for Q1 2026, down 17.98% year-over-year from $26.9 million in Q1 2025, and up 9.0% quarter-over-quarter from $20.3 million in Q4 2025.

Lexicon Pharmaceuticals (LXRX) Operating Expenses (2010 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has reported Operating Expenses for 17 consecutive years, with $22.1 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Expenses fell 17.98% year-over-year to $22.1 million; the TTM figure through Mar 2026 stood at $93.9 million (down 55.02% YoY), while the FY2025 annual figure was $98.7 million, down 56.74% from the prior year.
  • Operating Expenses rose to $22.1 million in Q1 2026 per LXRX's latest filing, from $20.3 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $65.4 million in Q3 2024 and bottomed at $20.3 million in Q4 2025.
  • Historically, Operating Expenses has averaged $36.6 million across 5 years, with a median of $30.3 million in 2022.
  • Annual changes were most pronounced in 2023 — Operating Expenses surged 115.24% — and 2025, when it plunged 65.81%.
  • Lexicon Pharmaceuticals' Operating Expenses stood at $30.3 million in 2022, then jumped by 56.53% to $47.4 million in 2023, then grew by 24.98% to $59.3 million in 2024, then slumped by 65.81% to $20.3 million in 2025, then climbed by 9.0% to $22.1 million in 2026.
  • Business Quant data shows LXRX's Operating Expenses at $22.1 million in Q1 2026, $20.3 million in Q4 2025, and $26.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 Lexicon Pharmaceuticals 1.04 Bn 846.13 Mn 653,000.00 27.23 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 27.23 Mn
Mar 31, 2026 22.10 Mn
Dec 31, 2025 20.27 Mn
Sep 30, 2025 26.37 Mn
Jun 30, 2025 25.13 Mn
Mar 31, 2025 26.94 Mn
Dec 31, 2024 59.29 Mn
Sep 30, 2024 65.44 Mn
Jun 30, 2024 57.00 Mn
Mar 31, 2024 46.46 Mn
Dec 31, 2023 47.44 Mn
Sep 30, 2023 49.79 Mn
Jun 30, 2023 44.56 Mn
Mar 31, 2023 31.17 Mn
Dec 31, 2022 30.31 Mn
Sep 30, 2022 23.13 Mn
Jun 30, 2022 24.04 Mn
Mar 31, 2022 23.42 Mn
Dec 31, 2021 25.34 Mn
Sep 30, 2021 22.99 Mn