Astrazeneca (AZN) Operating Expenses (2009 - 2026)

Astrazeneca (AZN) posted quarterly Operating Expenses of -$8.4 billion for Q1 2026, down 9.95% year-over-year from -$9.3 billion in Q1 2025, and up 10.07% on a QoQ basis from -$9.4 billion in Q4 2025.

Astrazeneca (AZN) Operating Expenses (2009 - 2026) Analysis & Trends

Astrazeneca (AZN) has reported Operating Expenses for 18 consecutive years, with -$8.4 billion the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Expenses fell 9.95% year-over-year to -$8.4 billion; the TTM figure through Mar 2026 stood at -$34.9 billion (down 2.93% YoY), while the FY2025 annual figure was $34.2 billion, up 1.8% from the prior year.
  • Operating Expenses came in at -$8.4 billion for Q1 2026 at Astrazeneca, up from -$9.4 billion in the prior quarter.
  • The five-year high for Operating Expenses was -$6.7 billion in Q1 2023, with the low at -$10.1 billion in Q4 2024.
  • Average Operating Expenses over 5 years is -$7.9 billion, with a median of -$7.7 billion recorded in 2023.
  • The largest YoY upside for Operating Expenses was 12.53% in 2022 against a maximum downside of 90.12% in 2022.
  • Year by year, Operating Expenses stood at -$7.2 billion in 2022, then retreated by 16.53% to -$8.4 billion in 2023, then dropped by 19.46% to -$10.1 billion in 2024, then climbed by 7.27% to -$9.4 billion in 2025, then grew by 10.07% to -$8.4 billion in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered -$8.4 billion, -$9.4 billion, and -$8.7 billion for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Eli Lilly 1,066.16 Bn 1,060.88 Bn 16.22 Bn 6.72 Bn
2 Johnson & Johnson 611.69 Bn 589.64 Bn 15.96 Bn 9.59 Bn
3 AbbVie 444.34 Bn 434.99 Bn 10.78 Bn 11.01 Bn
4 Astrazeneca 284.94 Bn 277.05 Bn 12.61 Bn -8.41 Bn
5 Merck 224.23 Bn 218.58 Bn 12.09 Bn 19.82 Bn
6 Amgen 195.12 Bn 183.08 Bn 5.87 Bn 5.95 Bn
7 Gilead Sciences 156.45 Bn 148.73 Bn 5.52 Bn 4.37 Bn
8 Pfizer 136.01 Bn 123.24 Bn -1.21 Bn 5.50 Bn
9 Novartis Ag 113.45 Bn 113.67 Bn - -
10 Biogen 30.87 Bn 26.59 Bn 1.82 Bn 2.10 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -8.41 Bn
Dec 31, 2025 -9.35 Bn
Sep 30, 2025 -8.75 Bn
Jun 30, 2025 -8.41 Bn
Mar 31, 2025 -7.65 Bn
Dec 31, 2024 -10.09 Bn
Sep 30, 2024 -8.26 Bn
Jun 30, 2024 -7.94 Bn
Mar 31, 2024 -7.28 Bn
Dec 31, 2023 -8.44 Bn
Sep 30, 2023 -7.38 Bn
Jun 30, 2023 -7.65 Bn
Mar 31, 2023 -6.67 Bn
Dec 31, 2022 -7.25 Bn
Sep 30, 2022 -6.74 Bn
Jun 30, 2022 -7.23 Bn
Mar 31, 2022 -6.97 Bn
Dec 31, 2021 -7.70 Bn
Sep 30, 2021 -7.70 Bn
Jun 30, 2021 -4.93 Bn