Pfizer (PFE) Operating Expenses (2009 - 2026)

Pfizer (PFE) posted quarterly Operating Expenses of $5.5 billion for Q1 2026, down 6.97% YoY from $5.9 billion in Q1 2025, and down 32.38% sequentially from $8.1 billion in Q4 2025.

Pfizer (PFE) Operating Expenses (2009 - 2026) Analysis & Trends

Pfizer has disclosed Operating Expenses across 18 years of filings, most recently posting $5.5 billion for Q1 2026.

  • In Q1 2026, Operating Expenses fell 6.97% year-over-year to $5.5 billion; the TTM figure through Mar 2026 stood at $25.4 billion (up 29.83% YoY), while the FY2025 annual figure was $25.8 billion, down 6.38% from the prior year.
  • Operating Expenses fell to $5.5 billion in Q1 2026, from $8.1 billion in the prior quarter.
  • Over the last five years, Operating Expenses for PFE reached as high as $9.0 billion in Q4 2023 and fell as low as $5.1 billion in Q2 2022.
  • The 5-year median for Operating Expenses is $6.1 billion (2022), against an average of $6.4 billion.
  • Annual changes were most pronounced in 2024 — Operating Expenses grew 19.64% — and 2025, when it fell 22.54%.
  • A 5-year view of Operating Expenses shows it stood at $6.3 billion in 2022, then surged by 43.37% to $9.0 billion in 2023, then sank by 31.47% to $6.2 billion in 2024, then soared by 32.15% to $8.1 billion in 2025, then plunged by 32.38% to $5.5 billion in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $5.5 billion, $8.1 billion, and $6.0 billion for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Eli Lilly 1,066.16 Bn 1,060.88 Bn 16.22 Bn 6.72 Bn
2 Johnson & Johnson 611.69 Bn 589.64 Bn 15.96 Bn 9.59 Bn
3 AbbVie 444.34 Bn 434.99 Bn 10.78 Bn 11.01 Bn
4 Astrazeneca 284.94 Bn 277.05 Bn 12.61 Bn -8.41 Bn
5 Merck 224.23 Bn 218.58 Bn 12.09 Bn 19.82 Bn
6 Amgen 195.12 Bn 183.08 Bn 5.87 Bn 5.95 Bn
7 Gilead Sciences 156.45 Bn 148.73 Bn 5.52 Bn 4.37 Bn
8 Pfizer 136.01 Bn 123.24 Bn -1.21 Bn 5.50 Bn
9 Novartis Ag 113.45 Bn 113.67 Bn - -
10 Biogen 30.87 Bn 26.59 Bn 1.82 Bn 2.10 Bn

Historic Data

Download Data
DateValue
Mar 29, 2026 5.50 Bn
Dec 31, 2025 8.13 Bn
Sep 28, 2025 5.97 Bn
Jun 29, 2025 5.82 Bn
Mar 30, 2025 5.91 Bn
Sep 29, 2024 6.16 Bn
Jun 30, 2024 7.52 Bn
Mar 31, 2024 6.00 Bn
Dec 31, 2023 8.98 Bn
Jul 2, 2023 6.28 Bn
Apr 2, 2023 5.88 Bn
Jul 3, 2022 6.05 Bn
Apr 3, 2022 5.09 Bn
Oct 3, 2021 6.22 Bn
Jul 4, 2021 5.16 Bn
Apr 4, 2021 4.79 Bn
Sep 27, 2020 4.95 Bn
Jun 28, 2020 5.08 Bn
Mar 29, 2020 4.25 Bn
Dec 31, 2019 5.11 Bn